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Impact of birthweight on health-care utilization during early childhood – a b...
Abstract Background Comprehensive data are needed to evaluate the burden of low birthweight. Analysis of routine data on health-care utilization during early childhood were used... -
Negative association between free triiodothyronine level and contrast-induced...
Abstract Background A low FT3 level is significantly associated with a variety of kidney disease and acute myocardial infarction (AMI). However, it remains unclear whether low... -
mTOR transcriptionally and post-transcriptionally regulates Npm1 gene express...
The mammalian target of rapamycin (mTOR) plays essential roles in the regulation of growth-related processes such as protein synthesis, cell sizing and metabolism in both normal... -
Regulatory crosstalk between type I and type II toxin-antitoxin systems in th...
We discovered a chromosomal locus containing 2 toxin-antitoxin modules (TAs) with an antisense transcriptional organization in the E. faecalis clinical isolate V583. These TAs... -
Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in...
Abstract Background Three-dimensional (3D) floating culture clumps of mesenchymal stem cell (MSC)/extracellular matrix (ECM) complexes (C-MSCs) consist of cells and... -
The Contribution of Dr. Charles West to the Development of Contemporary Healt...
Professors Festini and Glasper discuss the significant contribution of Dr Charles West to the development of paediatrics and children’s nursing during the 19th century and... -
Involvement of MAK-1 and MAK-2 MAP kinases in cell wall integrity in <i>Neuro...
Among three MAPK disruptants of Neurospora crassa, Δmak-1 was sensitive and Δmak-2 was hypersensitive to micafungin, a beta-1,3-glucan synthase inhibitor, than the wild-type or... -
Efficacy, tolerability and safety of darbepoetin alfa injection for the treat...
Abstract Background Darbepoetin alfa (DA-α) is a long-acting erythropoiesis-stimulating glycoprotein which has half-life three-fold longer than that of Erythropoietin alfa... -
Pulmonary artery catheter use in adult patients undergoing cardiac surgery: a...
Abstract Background The utility of pulmonary artery catheters (PACs) and their measurements depend on a variety of factors including data interpretation and personnel training.... -
Transcriptome analysis unravels spatiotemporal modulation of phytohormone-pat...
Abstract Background Gibberellin (GA) treatments can induce parthenocarpy in the main crop of San Pedro-type figs, the native non-parthenocarpic fruit, however, the underlying... -
Drosophila Netrin-B controls mushroom body axon extension and regulates court...
Abstract Mushroom body (MB) is a prominent structure essential for olfactory learning and memory in the Drosophila brain. The development of the MB involves the appropriate... -
Elevated D-dimer is associated with increased 28-day mortality in acute-on-ch...
Abstract Background Acute-on-chronic liver failure (ACLF) is a syndrome characterized by profound disrupted coagulation and fibrinolysis. Fibrinolytic marker D-dimer is... -
Serum of patients with active rheumatoid arthritis inhibits differentiation o...
Delayed fracture healing is frequently experienced in patients with systemic inflammation such as during rheumatoid arthritis (RA). The reasons for this are diverse, but could... -
The past, present and future of anti-malarial medicines
Abstract Great progress has been made in recent years to reduce the high level of suffering caused by malaria worldwide. Notably, the use of insecticide-treated mosquito nets... -
Newborn care practices and its determinants among postnatal mothers in Dessie...
Abstract Objective Newborn care practices like the initiation of breastfeeding within an hour, delay baby bathing, cord cutting with a safe instrument, and thermal care is a... -
Outcomes of follow-up care after an emergency department visit among pediatri...
Background and Objectives: Asthma exacerbations frequently trigger emergency department (ED) visits. Guidelines recommend timely follow-up after an ED visit for asthma, however,... -
Non-canonical Drosophila X chromosome dosage compensation and repressive topo...
Abstract Background In animals with XY sex chromosomes, X-linked genes from a single X chromosome in males are imbalanced relative to autosomal genes. To minimize the impact of... -
Population-based trends and risk factors of early- and late-onset preeclampsi...
Abstract Background Preeclampsia, a multisystem disorder in pregnancies complicates with maternal and fetal morbidity. Early- and late-onset preeclampsia, defined as... -
Roles of alternative splicing in modulating transcriptional regulation
Abstract Background The ability of a transcription factor to regulate its targets is modulated by a variety of genetic and epigenetic mechanisms. Alternative splicing can... -
SOX30 is a key regulator of desmosomal gene suppressing tumor growth and meta...
Abstract Background The expression of desmosomal genes in lung adenocarcinoma and lung squamous carcinoma is different. However, the regulatory mechanism of desmosomal gene...
