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A systematic review of the clinical presentation, treatment and relapse chara...
Abstract Background Despite increased efforts to control and ultimately eradicate human malaria, Plasmodium ovale malaria is for the most part outside the focus of research or... -
Subjective safety and self-confidence in prehospital trauma care and learning...
Abstract Background Prehospital trauma care is stressful and requires multi-professional teamwork. A decrease in the number of accident victims ultimately affects the routine... -
Safety and efficacy of the choline analogue SAR97276 for malaria treatment: r...
Abstract Background Malaria remains one of the most important infectious diseases. Treatment options for severe malaria are limited and the choline analogue SAR97276A is a novel... -
Open-label, multicenter, single-arm phase II DeCOG-study of ipilimumab in pre...
Abstract Background Ipilimumab is an approved immunotherapy that has shown an overall survival benefit in patients with cutaneous metastatic melanoma in two phase III trials. As... -
Development of the "Treatment beliefs in knee and hip OsteoArthritis (TOA)" q...
Abstract Background Use of conservative treatment modalities in osteoarthritis (OA) is suboptimal, which appears to be partly due to patients’ beliefs about treatments. The aim... -
CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development
Abstract Background Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe... -
Long-term safety and efficacy of vismodegib in patients with advanced basal c...
Abstract Background In the primary analysis of the ERIVANCE BCC trial, vismodegib, the first US Food and Drug Administration–approved Hedgehog pathway inhibitor, showed... -
NIRS-based neurofeedback training in a virtual reality classroom for children...
Abstract Background Children with attention-deficit/hyperactivity disorder (ADHD) suffer from attention deficits, motor hyperactivity, and impulsive behaviour. These impairments... -
Vision-related quality of life in patients receiving intravitreal ranibizumab...
Abstract Background Vision-related quality of life (vrQoL) is advancing more and more into the focus of interest in ophthalmological clinical research. However, to date only... -
A randomised, double-blind clinical phase II trial of the efficacy, safety, t...
Abstract Background The clinical development of a single encounter treatment for uncomplicated malaria has the potential to significantly improve the effectiveness of... -
Microdeletions in 9q33.3-q34.11 in five patients with intellectual disability...
Abstract Background Most microdeletions involving chromosome sub-bands 9q33.3-9q34.11 to this point have been detected by analyses focused on STXBP1, a gene known to cause early... -
Complementary and alternative medicine (CAM) as part of primary health care i...
Abstract Background In Germany, complementary and alternative medicine (CAM) in primary health care is offered by general practitioners (GPs) and by natural health... -
Equity in access to health care among asylum seekers in Germany: evidence fro...
Abstract Background Research on inequities in access to health care among asylum-seekers has focused on disparities between asylum-seekers and resident populations, but little... -
Inpatient gradual diagnostics and its relevance for determining treatment str...
Abstract Background Identifying patients who will benefit from spine surgery is still a challenge. This is especially the case when patients’ complaints and medical history,...
