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On the Stereospecific Conversion of Proximally-Oxygenated Trisubstituted Viny...
Allylically oxygenated vinyl α-triphenylstannanes such as 22 can be readily converted into vinyl iodides and thereafter stereodefined trisubstituted alkenes with retention of... -
Release of Nitrosating Species in the Course of Reduction of Benzo-1,2,3,4-te...
The reduction of benzo-1,2,3,4-tetrazine 1,3-dioxides (BTDOs) 1 with Na2S2O4 or SnCl2 is suggested to proceed via intermediate N-nitrosobenzotriazoles 3 to afford benzotriazoles... -
Construction of Novel Polycyclic Ring Systems by Transition-Metal-Catalyzed C...
Construction of Novel Polycyclic Ring Systems by Transition-Metal-Catalyzed Cycloisomerization of Ene−Ene−Ynes. Interception of a Carbenoid Intermediate in Skeletal... -
Sagittamides A and B. Polyacetoxy Long-Chain Acyl Amino Acids from a Didemnid...
An unidentified tunicate from Pohnpei, Micronesia, yielded sagittamides A and Bcompounds comprising a long-chain C26 dicarboxylic acid that acylates terminal l-valine and... -
Nitration of the tumor suppressor protein, p53, at tyrosine 327 promotes p53 ...
Previous studies demonstrate that nitric oxide (NO) promotes p53 transcriptional activity by a classical DNA damage responsive mechanism involving activation of ATM/ATR and... -
Tunability of Supramolecular Kagome Lattices of Magnetic Phthalocyanines Usin...
Self-assembly of various phthalocyanine (Pc) molecules and a derivative on an epitaxial graphene monolayer (MG) has been investigated by means of in situ ultrahigh vacuum... -
Rational Designs for Highly Proton-Conductive Metal−Organic Frameworks
A novel metal−organic framework (MOF), (NH4)2(adp)[Zn2(ox)3]·3H2O (1) was synthesized and its structure was determined. We propose three types of rational design to introduce... -
A Theoretical Study of the Chorismate Synthase Reaction
: Density functional calculations (B3LYP/6-31+G(d,p)) were carried out to investigate the mechanism of the anti-1,4-elimination of phosphate from... -
The Linkage of Catalysis and Regulation in Enzyme Action. Fluoropyruvate as a...
Pyruvate decarboxylase, a thiamin-diphosphate (ThDP) dependent enzyme from the yeast Saccharomyces cerevisiae (SCPDC), catalyzes the conversion of fluoropyruvate to carbon... -
Amphiphilic Janus Gold Nanoparticles via Combining "Solid-State Grafting-to" ...
Despite the great efforts that have been made toward obtaining Janus architectures, synthesizing sub-10 nanometer Janus nanoparticles (NPs) modified with different types of... -
High Performance n-Type Organic Field-Effect Transistors Based on π-Electroni...
Novel π-electron systems with trifluoromethylphenyl groups and/or a thiazolothiazole unit were developed as n-type semiconductors for OFETs. They showed excellent n-type... -
Engineering the enolase magnesium II binding site: implications for its evolu...
The glycolytic enzyme enolase catalyzes the reversible elimination of water from 2-phosphoglycerate (2-PGA) to form phosphoenolpyruvate (PEP). Two magnesium ions in the active... -
Solid-Phase Synthesis of Bicyclic Dipeptide Mimetics by Intramolecular Cycliz...
A general strategy for the solid-phase synthesis of structurally diverse bicyclic dipeptide mimetics is presented. Depending on the amino acid side-chain (R1), peptide-derived... -
Mechanism of Hydrogen Sorption in Single-Walled Carbon Nanotubes
Mechanism of Hydrogen Sorption in Single-Walled Carbon Nanotubes -
Modulation of T2 Relaxation Time by Light-Induced, Reversible Aggregation of ...
A reversible T2 contrast agent consisting of cross-linked anionic dextran coated iron oxide nanoparticles covalently coupled to a light-sensitive spiropyran (SP)/merocyanine... -
Solid-Phase Synthesis of Bis-2-imidazolidinethiones from Resin-Bound Tripeptides
The exhaustive reduction of resin-bound tripeptides with borane afforded three secondary amines and one primary amine. The treatment of the solid-support polyamines with... -
Bimetallic Catalysis for Styrene Homopolymerization and Ethylene−Styrene Copo...
This communication reports the styrene homopolymerization behavior and ethylene−styrene copolymerization behavior of the covalently linked bimetallic constrained geometry... -
Pressure-Induced Amorphization and Porosity Modification in a Metal−Organic F...
The impact of modest, industrially accessible pressures (0−1.2 GPa) on the structure and porosity of the zeolitic imidazolate framework Zn(2-methylimidazole)2, ZIF-8, was... -
Coibamide A, a Potent Antiproliferative Cyclic Depsipeptide from the Panamani...
Coibamide A (1) is a new, potent antiproliferative depsipeptide which was isolated from a marine Leptolyngbya cyanobacterium collected from the Coiba National Park, Panama. The... -
Domino Coupling Relay Approach to Polycyclic Pyrrole-2-carboxylates
CuBr2-catalyzed three-component coupling of N-benzylallylamine, ethyl glyoxalate, and terminal alkynes afforded glycine-tethered 1,6-enynes, which were further transformed into...
