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r37980778c78--a40d986ef1025d19d9685143933b56e4
Using dendrimers in cancer therapy as nonviral vectors for gene delivery seems promising. The biological performance of a dendrimer-based gene delivery system depends heavily on... -
dedup_wf_001--4edd6b37544e4fc6acb3bb4fce0088b7
A major bottleneck for the exploitation of data from the Kepler mission for stellar astrophysics and exoplanet research has been the lack of precise radii and evolutionary... -
r37980778c78--56fcee8741a21a8729fa2db393bd30b0
Design, synthesis, and in vitro bioevaluation of a new class of potential dual PPARα and γ agonists discovered through a structure-driven design paradigm are described. The... -
r37980778c78--5021c87261f3e825dde9a93ad9814f8e
To develop a novel antipsychotic agent which is an agonist of dopamine (DA) autoreceptors and an antagonist of postsynaptic DA receptors, a series of 7-[4-[4-(substituted... -
r37980778c78--20d5cb9ef2131f7c2f5fd1f5ab7c3f3a
The development of n-pentenyl furanosyl donors has been tested using arabinose as a model. The readily prepared ortho ester (NPOE) is converted into disarmed (NPGAC) and thence... -
Aryl Bridged 1-Hydroxypyridin-2-one: Effect of the Bridge on the Eu(III) Sens...
The efficiency of Eu3+ luminescence by energy transfer from an antenna ligand can be strongly dependent on the metal ion coordination geometry. The geometric component of the... -
Design and Synthesis of 5‘-Deoxy-5‘-Phenyladenophostin A, a Highly Potent IP<...
5‘-Deoxy-5‘-phenyladenophostin A (5), designed as a useful IP3 receptor ligand based on the previous structure−activity relationship studies, was successfully synthesized via... -
dedup_wf_001--9767c68d06d859f6b9375220af68b101
Table. Anthropometry, body composition and biochemical data of women who underwent Roux in Y gastric bypass and normal weight controls. (DOCX 19 kb) -
OpenIng – Open Access und Open Educational Resources in den Ingenieurwissensc...
Wie nutzen Ingenieurwissenschaftler_innen Open Access und Open Educational Resources und warum tun Sie es unter Umständen noch nicht? Diese Frage steht im Fokus des vom... -
r37980778c78--fe4e83e064bdf00dc834ea490c40288c
A ratiometric fluorescent biosensor for Hg2+ is constructed from the MerR protein and a duplex DNA containing a pyrene excimer. -
Mechanism of the Gold-Catalyzed Rearrangement of (3-Acyloxyprop-1-ynyl)oxiran...
The three competing paths for the rearrangement of 1 (involving 1,2- and 1,3-ester migration with alkyne or oxirane activation) evidence the multifaceted character of gold as a... -
Thermal Degradation of Designed Carbohydrate <i>N</i>-Oxides: A Single Metho...
Thermal Degradation of Designed Carbohydrate N-Oxides: A Single Methodology for the Synthesis of Ketoses, Enol Ethers, and Branched-Chain Sugars from N-Oxides Derived from... -
Design and Synthesis of Potent Cystine-Free Cyclic Hexapeptide Agonists at th...
Cyclic hexapeptides, incorporating a dipeptide unit in place of the disulfide bond found in urotensin, were prepared and screened at the human urotensin receptor. The bridging... -
1,1-Dichloroethene as a Predominant Intermediate of Microbial Trichloroethene...
A microbial culture derived from a landfill site in Dover, DE consistently reduced trichloroethene (TCE) to ethene through 1,1-dichloroethene (DCE) as a dominant intermediate in... -
In vitro and In vivo Optical Imaging Using Water-Dispersible, Noncytotoxic, L...
A facile method for synthesis of monodisperse, biocompatible, silica coated CdSe/CdS/ZnS quantum rods (QRs) and their use as probes for in vitro and in vivo optical bioimaging... -
Hybrid-DFT Study on Electronic Structures of the Active Site of Sweet Potato ...
The electronic structure and magnetic interactions of the active site of sweet potato purple acid phosphatase (PAP) were investigated by using UHF, pure DFT (UBLYP), and hybrid... -
Novel Amphiphilic Conetworks Composed of Telechelic Poly(ethylene oxide) and ...
Amphiphilic conetworks (APCNs) containing covalently bonded hydrophilic poly(ethyleneoxide) (PEO) and hydrophobic polyisobutylene (PIB) have been synthesized by chain end... -
Additional file 9: Figure S8. of Aneuploidy screening of embryonic stem cell ...
Multiplex assays of a euploid and a trisomic ES cell clone. Chr 8 and Chr 11 were assayed each in duplex with a reference gene assay as internal calibrator (Dot1l) (A, B, G, H)... -
Mitochondrial Complex I Subunits Are Decreased in Murine Nonalcoholic Fatty L...
We investigate the cause of the low activity of mitochondrial complex I found in ob/ob mice with nonalcoholic fatty liver disease. In mitochondrial proteins from ob/ob mice, we... -
One-Hydrogen Polarization in Hydroformylation Promoted by Platinum−Tin and Ir...
The first use of parahydrogen-induced polarization (PHIP) in hydroformylation is described including a novel one-hydrogen polarization (oneH-PHIP) in the product RCHO proton....
