818 items found

Types: publication Groups: Open Access Tags: Cell Biology Genetics Immunology

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  • publication

    r37980778c78--a40d986ef1025d19d9685143933b56e4

    Using dendrimers in cancer therapy as nonviral vectors for gene delivery seems promising. The biological performance of a dendrimer-based gene delivery system depends heavily on...
  • publication

    Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,...

    Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to eliminate potential in vivo hydrolysis to a...
  • publication

    <i>N</i>-Phenylphenylglycines as Novel Corticotropin Releasing Factor Recepto...

    Screening of a computationally designed synthetic library led to the discovery of the N-phenylphenylglycines (NPPGs) as a novel class of human corticotropin releasing factor...
  • publication

    dedup_wf_001--4edd6b37544e4fc6acb3bb4fce0088b7

    A major bottleneck for the exploitation of data from the Kepler mission for stellar astrophysics and exoplanet research has been the lack of precise radii and evolutionary...
  • publication

    dedup_wf_001--50baff3bcc3162f2bac15948284858b2

    Several events occurring during the secondary damage of traumatic brain injury (TBI) can cause oxidative stress. F2-isoprostanes (F2-IsoPs) and F4-neuroprostanes (F4-NPs) are...
  • publication

    Nitration of the tumor suppressor protein, p53, at tyrosine 327 promotes p53 ...

    Previous studies demonstrate that nitric oxide (NO) promotes p53 transcriptional activity by a classical DNA damage responsive mechanism involving activation of ATM/ATR and...
  • publication

    Discovery of Potent 3,5-Diphenyl-1,2,4-oxadiazole Sphingosine-1-phosphate-1 (...

    A class of 3,5-diphenyl-1,2,4-oxadiazole based compounds have been identified as potent sphingosine-1-phosphate-1 (S1P1) receptor agonists with minimal affinity for the S1P2 and...
  • publication

    Selective Oxidation of Hydroxy Groups of Bafilomycin A<sub>1</sub>

    Selective Oxidation of Hydroxy Groups of Bafilomycin A1
  • publication

    Metal−Metal Multiple Bonds in Early/Late Heterobimetallics Support Unusual Tr...

    Reduction of Zr/Co heterobimetallic complexes ICo(MesNPiPr2)3ZrCl (1) and ICo(iPrNPiPr2)3ZrCl (2) with excess Na/Hg under N2, followed by subsequent benzene extraction to remove...
  • publication

    dedup_wf_001--1267f88dc9dab84c2df43cf8151d0f07

    Mass spectrometry analysis of rhSIRPA protein. Table S2. Mass spectrometry analysis of calibrator from SIRPA ELISA kit (Cusabio). Table S3. Mass spectrometry analysis of...
  • publication

    dedup_wf_001--3d4c11cbc2adf1752d06bf9a7788afb6

    Transcription of GFP gene in leaves of selected Arabidopsis thaliana transformants with pER8-GFP. RT-qPCR analysis of transcript levels in five selected lines untreated with...
  • publication

    dedup_wf_001--71799db0a97d7a4a75f6410ed20b9acc

    Laser microdissection (LMD) is a tool that is used in forensic laboratories for the analysis of DNA from specifically targeted cells. Since 2010, the Institute of Environmental...
  • publication

    Additional file 3 of Unraveling the molecular interactions involved in phase ...

    Additional file 3: Supplementary Fig. S2. Related to Fig. 1. Representative images of U2OS cells expressing GFP-GR incubated with Dex, before and after incubation with 3 or 10%...
  • publication

    Additional file 1: Figure S1. of Isolation and characterization of chromosoma...

    PpCR-1 monomer hunting from the amplified sequence by designated primers of clone 6. Figure S2. PpTR-1 monomer hunting from the amplified sequence by designated primers of clone...
  • publication

    r37980778c78--45c77806280e278526960e808d2b7b2b

    Electrolysis of benzylthiocyanate, benzyl chloride, p-methylbenzyl chloride, p-methoxybenzyl chloride, or toluene in acetonitrile, at platinum electrodes in a two compartments...
  • publication

    r37980778c78--22558a45fd45bae984195b836bb479a9

    Dioxygen Activation under Ambient Conditions: Cu-Catalyzed Oxidative Amidation−Diketonization of Terminal Alkynes Leading to α-Ketoamides
  • publication

    Additional file 1 of The importance of censoring in competing risks analysis ...

    Simulating proportional subdistribution hazards. Describes an algorithm for simulating survival data with competing risks under a proportional subdistribution hazards model with...
  • publication

    Novel 2,3-Dihydrobenzofuran-2-carboxylic Acids:  Highly Potent and Subtype-Se...

    The design and synthesis of a novel class of 2,3-dihydrobenzofuran-2-carboxylic acids as highly potent and subtype-selective PPARα agonists are reported. Systematic study of...
  • publication

    Finding and Accessing "Small" Data through SAGE

    Presentation on the Secondary Analysis to Generate Evidence (SAGE) collaborative platform and how it relates to the Accessibility aspect of the FAIR Principles. For the National...
  • publication

    dedup_wf_001--28495ba915027accb81b8c3f8c97d24a

    Bacterial load of Drosophila melanogaster after septic injury with Staphylococcus aureus. Drosophila were harvested each 24 h following the induction of sepsis induced by S....