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Two subphenotypes of septic acute kidney injury are associated with different...
Abstract Background The pathophysiology of septic acute kidney injury is inadequately understood. Recently, subphenotypes for... -
A global sensitivity analysis approach for morphogenesis models
Abstract Background Morphogenesis is a developmental process in which cells organize into shapes and patterns. Complex, non-linear and multi-factorial models with images as... -
An inventory of collaborative medication reviews for older adults - evolution...
Abstract Background Collaborative medication review (CMR) practices for older adults are evolving in many countries. Development has been under way in Finland for over a... -
PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma
Abstract Background The Wnt/β-catenin pathway has a key role in regulating cellular processes and its aberrant signaling can lead... -
Untapped potential of multicenter studies: a review of cardiovascular risk pr...
Abstract Background Clinical prediction models are often constructed using multicenter databases. Such a data structure poses additional challenges for statistical analysis... -
Abdominal obesity increases metabolic risk factors in non-obese adults: a Hun...
Abstract Background The prevalence of abdominal obesity is increasing worldwide. Adults with abdominal obesity have been reported to have increased risk of cardiometabolic... -
A combined epigenome- and transcriptome-wide association study of the oral ma...
Abstract Background The oral mucosa has an important role in maintaining barrier integrity at the gateway to the gastrointestinal and respiratory tracts. Smoking is a strong... -
Reduced endogenous secretory RAGE in blood and bronchoalveolar lavage fluid i...
Abstract Background The endogenous secretory receptor for advanced glycation end products (esRAGE) is a soluble isoform produced by alternative splicing of the RAGE gene. The... -
Phosphorylation of NFATC1 at PIM1 target sites is essential for its ability t...
Abstract Background Progression of prostate cancer from benign local tumors to metastatic carcinomas is a multistep process. Here... -
Physiologically variable ventilation reduces regional lung inflammation in a ...
Abstract Background Benefits of variable mechanical ventilation based on the physiological breathing pattern have been observed both in healthy and injured lungs. These benefits... -
Serum brain-derived neurotrophic factor (BDNF) is not regulated by testostero...
Abstract Brain morphology significantly differs between the sexes. It has been shown before that some of these differences are attributable to the sex-specific hormonal milieu.... -
Bi-directional prospective associations between objectively measured physical...
Abstract Background The direction of the longitudinal relationship between physical activity (PA) and fundamental motor skills (FMS) remains unclear. We evaluated the...
