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Real world experience of patients with amyotrophic lateral sclerosis (ALS) in...
Background: Treatment of spasticity poses a major challenge in amyotrophic lateral sclerosis (ALS) patient management. Delta-9-tetrahydrocannabinol (THC):cannabidiol (CBD)... -
A systematic literature review of reviews on techniques for physical activity...
Abstract The links between increased participation in Physical Activity (PA) and improvements in health are well established. As this body of evidence has grown, so too has the... -
The efficacy of varenicline in achieving abstinence among waterpipe tobacco s...
Abstract Background Waterpipe tobacco smoking has increased among youth across the globe including in the US, and it continues as a common and traditional form of smoking... -
Prioritising pathogens for the management of severe febrile patients to impro...
Abstract Background Severe febrile illness without a known source (SFWS) is a challenge for clinicians when deciding how to manage a patient, particularly given the wide... -
Cord blood DNA methylation reflects cord blood C-reactive protein levels but ...
Abstract Background Prenatal inflammation has been proposed as an important mediating factor in several adverse pregnancy outcomes. C-reactive protein (CRP) is an inflammatory... -
Sitagliptin does not reduce the risk of cardiovascular death or hospitalizati...
Abstract Background To examine the effects of the DPP-4i sitagliptin on CV outcomes during and after incident MI in the Trial... -
Scaling up strategies of the chronic respiratory disease programme of the Eur...
Abstract Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care... -
Predictors of delayed culture conversion among Ugandan patients
Abstract Background Estimates of month-2 culture conversion, a proxy indicator of tuberculosis (TB) treatment efficacy in phase-2 trials can vary by culture-type and... -
Applying GRADE-CERQual to qualitative evidence synthesis findings: introducti...
Abstract The GRADE-CERQual (‘Confidence in the Evidence from Reviews of Qualitative research’) approach provides guidance for assessing how much confidence to place in findings... -
Pharmacological pain relief and fear of childbirth in low risk women; seconda...
Abstract Background Fear of childbirth may reduce the womens’ pain tolerance during labour and may have impact on the mother-infant interaction. We aimed to assess (1) the... -
Introduction of a standardised protocol, including systematic use of tranexam...
Abstract Background Bleeding is an important cause of death in trauma victims. In 2010, the CRASH-2 study, a multicentre randomized control trial on the effect of tranexamic... -
Concurrent use of prescription drugs and herbal medicinal products in older a...
Background: There has been a global increase in the use of herbal medicinal products (HMPs). About a quarter of UK adults use HMPs, bought over the counter by self-prescription... -
Outcome reporting in neonates experiencing withdrawal following opioid exposu...
Abstract Background Neonatal withdrawal secondary to in utero opioid exposure is a growing global concern stressing the psychosocial well-being of affected families and scarce... -
The burden, epidemiology, costs and treatment for Duchenne muscular dystrophy...
Abstract Background Duchenne Muscular Dystrophy (DMD) is a rapidly progressive, lethal neuromuscular disorder, present from birth, which occurs almost exclusively in males. We... -
Assessing and developing the written reflective practice skills of speech-lan...
Purpose: Written reflective practice aims to support critical thinking and problem solving skills in speech-language pathology (SLP) clinical education programmes. Yet, there... -
Estimating mean circulatory filling pressure in clinical practice: a systemat...
Abstract The bedside hemodynamic assessment of the critically ill remains challenging since blood volume, arterialâ venous interaction and compliance are not measured directly.... -
Dyskinesia and brain-derived neurotrophic factor levels after long-term levod...
Abstract Background The treatment of Parkinson’s disease is often complicated by levodopa-induced dyskinesia (LID). Nicotinic... -
Health and educational aspirations in adolescence: a longitudinal study in Fi...
Abstract Background The health selection hypothesis suggests that poor health leads to low educational attainment during the life... -
Determining ‘curriculum viability’ through standards and inhibitors of curric...
Abstract Background A curriculum is dynamic entity and hence, metaphorically, can be considered ‘alive’. Curricular diseases may impair its quality and hence its viability. The... -
Applying GRADE-CERQual to qualitative evidence synthesis findings—paper 4: ho...
Abstract Background The GRADE-CERQual (Grading of Recommendations Assessment, Development and Evaluation-Confidence in Evidence from Reviews of Qualitative research) approach...
