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A global sensitivity analysis approach for morphogenesis models
Abstract Background Morphogenesis is a developmental process in which cells organize into shapes and patterns. Complex, non-linear and multi-factorial models with images as... -
Comparative and selection sweep analysis of CNV was associated to litter size...
This study aims to identify the relative Copy number variation (CNV) associated with the litter size of Dazu black goats based on the unpublished CNV analytical results of our... -
PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma
Abstract Background The Wnt/β-catenin pathway has a key role in regulating cellular processes and its aberrant signaling can lead... -
Abdominal obesity increases metabolic risk factors in non-obese adults: a Hun...
Abstract Background The prevalence of abdominal obesity is increasing worldwide. Adults with abdominal obesity have been reported to have increased risk of cardiometabolic... -
A combined epigenome- and transcriptome-wide association study of the oral ma...
Abstract Background The oral mucosa has an important role in maintaining barrier integrity at the gateway to the gastrointestinal and respiratory tracts. Smoking is a strong... -
Evaluation of whole exome sequencing as an alternative to BeadChip and whole ...
Abstract Background Understanding the underlying genetic structure of human populations is of fundamental interest to both biological and social sciences. Advances in... -
Reduced endogenous secretory RAGE in blood and bronchoalveolar lavage fluid i...
Abstract Background The endogenous secretory receptor for advanced glycation end products (esRAGE) is a soluble isoform produced by alternative splicing of the RAGE gene. The... -
Cold seawater induces early sexual developmental stages in the BPG axis of Eu...
Abstract Background The impossibility of closing the life cycle of the European eel (Anguilla anguilla) in captivity troubles the future of this critically endangered species.... -
Phosphorylation of NFATC1 at PIM1 target sites is essential for its ability t...
Abstract Background Progression of prostate cancer from benign local tumors to metastatic carcinomas is a multistep process. Here... -
A transcriptomic snapshot of early molecular communication between Pasteuria ...
© The Author(s). 2018 -
Biallelic modification of IL2RG leads to severe combined immunodeficiency in ...
Background: Pigs with SCID can be a useful model in regenerative medicine, xenotransplantation, and cancer cell transplantation studies. Utilizing genome editing technologies... -
ショウジョウバエ野外集団におけるコアプロモーター配列変異によって生じる発現量変化への自然選択
Abstract Background Understanding the evolutionary forces that influence variation in gene regulatory regions in natural populations is an important challenge for evolutionary...
