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Two subphenotypes of septic acute kidney injury are associated with different...
Abstract Background The pathophysiology of septic acute kidney injury is inadequately understood. Recently, subphenotypes for... -
Immune responses upon Campylobacter jejuni infection of secondary abiotic mic...
Abstract Background Campylobacter jejuni infections are of rising importance worldwide. Given that innate immune receptors including nucleotide-oligomerization-domain-2 (Nod2)... -
A specific synbiotic-containing amino acid-based formula in dietary managemen...
Here we report follow-up data from a double-blind, randomized, controlled multicenter trial, which investigated fecal microbiota changes with a new amino acid-based formula... -
Cord blood DNA methylation reflects cord blood C-reactive protein levels but ...
Abstract Background Prenatal inflammation has been proposed as an important mediating factor in several adverse pregnancy outcomes. C-reactive protein (CRP) is an inflammatory... -
Serum sodium and intracranial pressure changes after desmopressin therapy in ...
Abstract Background In traumatic brain injury (TBI) patients desmopressin administration may induce rapid decreases in serum... -
PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma
Abstract Background The Wnt/β-catenin pathway has a key role in regulating cellular processes and its aberrant signaling can lead... -
Role of goblet cell protein CLCA1 in murine DSS colitis
Abstract Background The secreted goblet cell protein CLCA1 (chloride channel regulator, calcium-activated-1) is, in addition to its established role in epithelial chloride... -
Pharmacological pain relief and fear of childbirth in low risk women; seconda...
Abstract Background Fear of childbirth may reduce the womens’ pain tolerance during labour and may have impact on the mother-infant interaction. We aimed to assess (1) the... -
Genetic variants in SERPINA4 and SERPINA5, but not BCL2 and SIK3 are associat...
Abstract Background Acute kidney injury (AKI) is a multifactorial syndrome, but knowledge about its pathophysiology and possible... -
Subjective and objective assessment of physical activity in multiple sclerosi...
Abstract Background Physical activity (PA) is frequently restricted in people with multiple sclerosis (PwMS) and aiming to enhance PA is considered beneficial in this... -
Burden of acute kidney injury and 90-day mortality in critically ill patients
Abstract Background Mortality rates associated with acute kidney injury (AKI) vary among critically ill patients. Outcomes are often not corrected for severity or duration of... -
Occurrence of marked sepsis-induced immunosuppression in pediatric septic sho...
Abstract Background While the process of sepsis-induced immunosuppression is now well described in adults, very little information is available on immune functions in pediatric... -
Physiologically variable ventilation reduces regional lung inflammation in a ...
Abstract Background Benefits of variable mechanical ventilation based on the physiological breathing pattern have been observed both in healthy and injured lungs. These benefits... -
Aberrant intestinal microbiota due to IL-1 receptor antagonist deficiency pro...
Abstract Background Perturbation of commensal intestinal microbiota has been associated with several autoimmune diseases. Mice deficient in interleukin-1 receptor antagonist... -
Microarray expression studies on bone marrow of patients with Shwachman-Diamo...
We report the expression analysis of bone marrow (BM) cells of patients with Shwachman-Diamond syndrome (SDS), in relation to the presence of clonal chromosome anomalies:... -
Factors influencing patient and health care delays in Oropharyngeal Cancer
Abstract Background The incidence of human papillomavirus (HPV)–associated oropharyngeal squamous cell carcinoma (OPSCC) is increasing. Patients with HPV-associated and... -
The role of the intra-abdominal view in complicated intra-abdominal infections
Abstract Background The prognostic role of what a surgeon observes in the abdomen of patients with complicated intra-abdominal... -
Campylobacter jejuni infection of conventionally colonized mice lacking nucle...
Abstract Background The nucleotide-binding oligomerisaton protein 2 (NOD2) constitutes a pivotal sensor of bacterial muramyl dipeptide and assures expression of distinct... -
Diagnosis, treatment, and response assessment in solitary plasmacytoma: Updat...
Abstract Solitary plasmacytoma is an infrequent form of plasma cell dyscrasia that presents as a single mass of monoclonal plasma cells, located either extramedullary or... -
Digital breast tomosynthesis for breast cancer screening and diagnosis in wom...
Abstract Background This study aimed to systematically review and to meta-analyse the accuracy of digital breast tomosynthesis (DBT) versus digital mammography (DM) in women...
