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Antimalarial Peptides from Marine Cyanobacteria: Isolation and Structural Elu...
As part of a continuing program to identify novel treatments for neglected parasitic diseases, the Panama International Cooperative Biodiversity Group (ICBG) program has been... -
Eranthisaponins A and B, Two New Bisdesmosidic Triterpene Saponins from the T...
The present investigation aimed at the glycoside constituents of the tubers of Eranthis cilicica has resulted in the isolation of two new bisdesmosidic triterpene saponins based... -
Sphingolipids from Bombycis Corpus 101A and their neurotrophic effects.
Three new (2−4) and one known (1) sphingolipid were identified in the MeOH extract of Bombycis Corpus 101A. Their structures were elucidated as... -
Cytotoxic flavonoids from the fruits of <i>Derris indica</i>
Chemical investigation of the ethyl acetate extract from the fruits of Derris indica has led to the isolation of a new furanoflavonoid derivative, 4′-hydroxypinnatin (1), and... -
dedup_wf_001--886f8f80aadd55a5909b8ed7439bc722
Three new triterpenoid saponins, namely asprellinoids A–C (1–3), featuring a sulfate substitution in sugar moiety, were isolated from the stems of Ilex asprella (Hook. et Arn.)... -
Absolute Configuration of Brevisamide and Brevisin: Confirmation of a Univers...
The discovery of brevisin, the first example of an “interrupted” polycyclic ether, obtained from the dinoflagellate Karenia brevis, posed some important questions regarding the... -
Isolation and Structure Determination of Nostocyclopeptides A1 and A2 from th...
The isolation and total structure determination of nostocyclopeptides A1 (1) and A2 (2) are described. These cyclic heptapeptides, which possess a unique imino linkage in the... -
dedup_wf_001--ed9c504ff5a0d7ccf85bd2d191ce712a
As a part of our continuing research for bioactive constituents from Cynanchum limprichtii Schltr., two new C21 steroidal glycosides limproside A (1) and limproside B (2) were... -
Probing Biotransformation Relationships among Pyridoacridines by Focusing on ...
The presence of the MeO-5 in the structure 5-methoxyamphimidine (5) is unusual in the light of a recent analysis of the relationships among sponge- and tunicate-derived... -
Revisiting the Sponge Sources, Stereostructure, and Biological Activity of Cy...
The dramatic biogeographical variations in the secondary metabolites from Psammocinia aff. bulbosa have complicated our efforts to re-isolate the two most cytotoxic of its... -
Biosynthetic Evidence Supporting the Generation of Terpene Chemodiversity in ...
This paper reports the study of terpene biosynthesis in the marine nudibranch Doriopsilla pelseneeri. In vivo feeding experiments with 13C-glucose proved the de novo origin of... -
Absolute Configuration of Lippifoliane and Africanane Derivatives
The absolute configuration of naturally occurring lippifoliane derivatives isolated from the widely used plant Lippia integrifolia was assigned by analysis of the circular... -
Melanin Synthesis Inhibitors fromLespedeza cyrtobotrya
From the roots of Lespedeza cyrtobotrya, 45 flavonoids were isolated along with 20 new and 25 known compounds. Lipophilic flavonoids 2, 3, 7, 9, 11, 28, 30, and 39 exhibited... -
Isolation and Characterization of Tirandamycins from a Marine-Derived <i>Stre...
The novel dienoyl tetramic acids tirandamycin C (1) and tirandamycin D (2) with activity against vancomycin-resistant Enterococcus faecalis were isolated from the marine... -
Cytotoxic and Antimycobacterial Prenylated Flavonoids from the Roots of <i>Er...
Eight new prenylated flavonoids, khonklonginols A−H (1−8), together with six known compounds including five flavonoids, lupinifolinol (9), dehydrolupinifolinol (10), flemichin D... -
Pachastrissamine, a Cytotoxic Anhydrophytosphingosine from a Marine Sponge,Pa...
An anhydrophytosphingosine named pachastrissamine (3) has been isolated as a cytotoxic principle of a sponge, Pachastrissa sp., and the structure including the absolute... -
Structural and Stereochemical Reassessment of Sclerophytin-Type Diterpenes
A complete reassessment of the structural assignments of the sclerophytin diterpenes is provided. -
Diterpenoids and phenolic analogues from the roots of Aralia continentalis
Two new compounds, including a nor-pimarane diterpenoid (continentanol, 1) and a phenolic derivative (aralianic acid, 2), along with the known diterpenoids (3–11),... -
Cycloartane triterpenes from <i>Beesia calthaefolia</i> and their anticomplem...
Fifteen cycloartane triterpenes were isolated from Beesia calthaefolia and among them one was new cycloartane triterpenoid. The structure of new compound was determined by the... -
Grindelane Diterpenoids from <i>Stevia subpubescens</i>
Four new 9R,13R-epoxylabdane diterpenes (1−4) and a known clerodane derivative, 3,4β-epoxy-5β,10β-cis-17α,20α-clerod-13(14)-en-15,16-olide, were isolated from the leaves of...
