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Economic evaluation of nivolumab combined with ipilimumab in the first-line t...
The objective of this study was to evaluate the cost-effectiveness of nivolumab in combination with ipilimumab (nivo + ipi) compared to current therapeutic alternatives in... -
Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
dedup_wf_001--aad5de0a2207e226aec94d5ef408710b
A previous survey investigated postmenopausal vaginal atrophy in a sample of women across Latin America. To help implement a tailored approach to improve postmenopausal care and... -
Stroke rehabilitation research translation in Australia: a survey of clinical...
Translation of findings from stroke trials into clinical practice remains low. Little is known about planned translation activities from the perspective of trialists who... -
Medication therapy strategies for the coronavirus disease 2019 (COVID-19): re...
The coronavirus disease 2019 (COVID-19) pandemic has spread globally since it outbroke in December 2019. The urgent pandemic presents an unprecedented challenge to develop and... -
Burden of disease and costs associated with type 2 diabetes in emerging and e...
To estimate the clinical and economic burden of type 2 diabetes (T2D) in established (EST) and emerging markets (EMG). Three systematic literature reviews were conducted in... -
The economic burden of common adverse events associated with metastatic color...
Aims: Adverse events (AEs) associated with treatments for metastatic colorectal cancer (mCRC) may compromise the course of treatment, impact quality-of-life, and increase... -
Systematic literature review of the epidemiology and clinical burden of chron...
We conducted a systematic literature review (SLR) to determine the epidemiology and clinical burden of chronic rhinosinusitis with nasal polyps (CRSwNP) and to describe how the... -
Intravitreal aflibercept: its role in treatment of neovascular age-related ma...
Introduction: Age related macular degeneration (AMD) affects over 14 million people worldwide and is the commonest cause of visual loss in the over 65’s age group in the... -
Association of tenofovir disoproxil fumarate exposure with chronic kidney dis...
Tenofovir disoproxil fumarate (TDF)-based regimens have been associated with impaired kidney function and loss of bone mineral density among patients living with HIV (PLWH). We... -
dedup_wf_001--ec3619771e810a154c5d52d33605d6ab
OBJECTIVE To assess evidence on the safety and efficacy of ABVD (doxorubicin [Adriamycin®], bleomycin, vinblastine, and dacarbazine), BEACOPP (bleomycin, etoposide, doxorubicin,... -
Cost-effectiveness of pembrolizumab with axitinib as first-line treatment for...
Objective: Pembrolizumab/axitinib significantly prolonged overall survival (OS) and progression-free survival (PFS) and increased objective response rate versus sunitinib in the... -
dedup_wf_001--ea455f539951a52e0f341c03d5429003
This article examines the variation in income redistribution across autocracies. It argues that the degree of electoral uncertainty affects two mechanisms that shape the... -
dedup_wf_001--a35e03ea4a8f433445518894738e3a56
Emergency Departments (ED) are rapidly becoming an important location for initiation of buprenorphine (EDBUP) for the treatment of opioid use disorder (OUD). Previous... -
dedup_wf_001--b2aea697ee420d2a6a886a8155e8b204
The β-D-Mannuronic acid (M2000) as a novel immunosuppressive drug, patented (PCT/EP2017/067920), has shown positive effects in experimental model of multiple sclerosis (MS). In... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
Societal implications of medical insurance coverage for imatinib as first-lin...
Objectives: Imatinib (Glivec) and nilotinib (Tasigna) have been covered by critical disease insurance in Jiangsu province of China since 2013, which changed local treatment... -
The influence of driving anger on truck drivers’ speeding behavior in Serbia:...
OBJECTIVE Speeding behavior is recognized as one of the three main causes of risk on the roads and the most frequent ordinary violation among truck drivers. The study reported... -
Chronic use of statins and risk of post-endoscopic retrograde cholangiopancre...
There is limited evidence on the role of chronic statin therapy in the prevention of acute pancreatitis after ERCP. The aim of this meta-analysis was to evaluate the efficacy of... -
dedup_wf_001--509307ac0c6fdddd3073c05efaab8f8e
Marketing authorization holder (MAH)-sponsored patient support programs (PSPs) are a major source of adverse event (AE) reports. The impact of reports from PSPs on the ability...