-
Anti-malarial treatment outcomes in Ethiopia: a systematic review and meta-an...
Abstract Background Ethiopia is among countries with a high malaria burden. There are several studies that assessed the efficacy of anti-malarial agents in the country and this... -
Identifying targets for antibiotic stewardship interventions through analysis...
Abstract Background In order to change antibiotic prescribing behaviour, we need to understand the prescribing process. The aim of this study was to identify targets for... -
Repeated praziquantel treatment and Opisthorchis viverrini infection: a popul...
Abstract Background Opisthorchis viverrini infection is highly prevalent in northeast Thailand. This liver fluke is classified as a carcinogen due to its causal links with... -
A pilot feasibility randomised controlled trial of an adjunct brief social ne...
Abstract Background Approximately 3% of people receiving opioid substitution therapy (OST) in the UK manage to achieve abstinence from prescribed and illicit drugs within three... -
The Video intervention to Inspire Treatment Adherence for Life (VITAL Start):...
Abstract Background Improving maternal antiretroviral therapy (ART) retention and adherence is a critical challenge facing prevention of mother-to-child transmission (PMTCT) of... -
Risk factors for tuberculosis smear non-conversion in Eden district, Western ...
Abstract Background Tuberculosis (TB) continues to be a major global health problem. While progress has been made to improve TB cure rates, South Africa’s 76 % smear-positive... -
Patient’s perception of kidney stone prevention within the emergency departme...
Abstract Background No known data in the literature assessing practice of kidney stone prevention in the emergency department (ED) is available. Objectives Assess patient... -
User survey finds rapid evidence reviews increased uptake of evidence by Vete...
Abstract Background To provide evidence synthesis for faster-paced healthcare decision-making, rapid reviews have emerged as a streamlined alternative to standard systematic... -
Association between antibiotic consumption and the rate of carbapenem-resista...
Abstract Background This study aimed to investigate the relationship between the rate of carbapenem-resistant Gram-negative bacteria and antibiotic consumption intensity in 153... -
Regulation of STEP61 and tyrosine-phosphorylation of NMDA and AMPA receptors ...
Abstract Background Sustained changes in network activity cause homeostatic synaptic plasticity in part by altering the postsynaptic accumulation of N-methyl-D-aspartate... -
Downstream consequences of diagnostic error in pediatric anaphylaxis
Abstract Background Pediatric anaphylaxis is commonly misdiagnosed in the Emergency Department (ED). We aimed to determine the impact of inaccurate diagnosis on the management... -
Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-indu...
Abstract Background Although allergic asthma is a complex area with many interacting factors involved, the ‘hygiene hypothesis’ proposes that a lack of exposure to infection... -
Prevalence and social determinants of psychological distress among people who...
Abstract Background People who use drugs are at a disproportionately higher risk of mental disorders due to prolonged exposure to psychosocial challenges. However, studies on... -
UK national clinical audit: management of pregnancies in women with HIV
Abstract Background The potential for HIV transmission between a pregnant woman and her unborn child was first recognized in 1982. Since then a complex package of measures to... -
Impact of antibiotic therapy on the development and response to treatment of ...
Abstract Background The gut microbiome impacts the efficacy of immune checkpoint inhibitor (ICI) therapy and the development of ICI-mediated diarrhea and/or colitis (IMDC).... -
Using predicate and provenance information from a knowledge graph for drug ef...
Abstract Background Biomedical knowledge graphs have become important tools to computationally analyse the comprehensive body of biomedical knowledge. They represent knowledge... -
Comparison of anti-malarial drugs efficacy in the treatment of uncomplicated ...
Abstract Background Artemisinin-based combination therapy (ACT) and novel drug combinations are available and used in African countries to treat uncomplicated malaria. Network... -
A systematic review of clinical audit in companion animal veterinary medicine
Abstract Background Clinical audit is a quality improvement process with the goal of continuously improving quality of patient care as assessed by explicit criteria. In human... -
Pilot study comparing the Childhood Arthritis & Rheumatology Research All...
Abstract Objectives To assess the feasibility of studying the comparative effectiveness of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus treatment... -
HIV-1 integrase resistance associated mutations and the use of dolutegravir i...
Abstract Background Sub-Saharan Africa carries the greatest burden of HIV-infection with increasing drug resistance burden, which requires improved patient management and...
