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Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
Risk factors for poor asthma control and impaired quality of life in a Caribb...
Asthma, a major cause of disability and reduced quality of life, has a high global prevalence and burden of death. Despite the propitious guidelines, a substantial portion of... -
TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTOR...
Macroautophagy/autophagy is an evolutionarily conserved process that involves the selective degradation of cytoplasmic components within lysosomes in response to starvation.... -
Impacted foetal head at caesarean section: a national survey of practice and ...
This is a national survey of UK obstetric trainees and consultant labour ward leads designed to investigate the current practice and training for an impacted foetal head (IFH)... -
Association of tenofovir disoproxil fumarate exposure with chronic kidney dis...
Tenofovir disoproxil fumarate (TDF)-based regimens have been associated with impaired kidney function and loss of bone mineral density among patients living with HIV (PLWH). We... -
Impact of differential and time-dependent autophagy activation on therapeutic...
Activation of macroautophagy/autophagy, a key mechanism involved in the degradation and removal of aggregated proteins, can successfully reverse Huntington disease phenotypes in... -
dedup_wf_001--76d6c0849b62c1fb0e912d7290bfa4ad
Latinos are heavily affected with childhood asthma. Little is known about epigenetic mechanisms of asthma in Latino youth. We conducted a meta-analysis of two epigenome-wide... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
dedup_wf_001--5101a4e2d80df72a31b34d26c9459e57
A coke produced using a custom-built sole-heated oven and a coke prepared in a pilot-scale oven from a matched coal, were compared using a range of analytical techniques. The... -
S100A9/CD163 Expression in Circulating Classical Monocytes in Chronic Obstruc...
Although many studies have characterized polarity of macrophages in chronic obstructive pulmonary disease (COPD), limited information is available regarding cellular phenotypes... -
dedup_wf_001--53585fd2ae74e46f2b28de670d1bd787
This paper provides insights into trademark activity at the regional level via two objectives. First, it examines the relationship between technological capabilities and new... -
Methylation Status of VDR Gene and its Association with Vitamin D Status and ...
Deficiency in circulatory vitamin D level and vitamin D receptor DNA methylation could be associated with weakened innate immune response and increased susceptibility to... -
Molecular mechanism of microRNA-21 promoting Schwann cell proliferation and a...
At present, the functional recovery after nerve injury is not satisfactory in clinical practice. The aim of this study was to explore the molecular mechanism of miR-21 promoting... -
Determination of phthalate esters in breast milk before and after frozen stor...
This study describes the migration of 20 phthalates from breast milk storage bags to breast milk after storage frozen for 1 to 6 months. Analysis of the investigated phthalates... -
Implication of Size-Controlled Graphite Nanosheets as Building Blocks for The...
Preparation of three-dimensional (3-D) networks has received significant attention as an effective approach for applications involving transport phenomena, such as thermal... -
Comparison between insulin degludec/liraglutide treatment and insulin glargin...
ABSTRACTAim: To evaluate the efficacy and adverse effects of IDegLira and IGlarLixi treatment and to perform a comparison between two strategies.Methods: The registration number... -
The New Zealand white rabbit animal model of acute radiation syndrome: hemato...
Animal models that accurately reflect human responses to radiation injury are needed for advanced mechanistic investigation and development of effective therapeutics. The rabbit... -
miR-296-5p inhibits IL-1β-induced apoptosis and cartilage degradation in huma...
Osteoarthritis (OA) is characterized by apoptosis of chondrocytes and an imbalance of extracellular matrix (ECM) synthesis and catabolism. Emerging evidence has demonstrated... -
Organized crime, suspicious transaction reporting and anti-money laundering r...
This study investigates the efficiency of suspicious transaction reporting activity to a financial intelligence unit as a means to deter money laundering. Baseline and... -
dedup_wf_001--1fb2ffd1fd17c0219fd35fff5faf5a85
Exposure to ambient air pollutants such as ozone (O3) and particulate matter (PM) is associated with increased cardiovascular morbidity and rate of mortality, but the underlying...
