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Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammatio...
Abstract Background The interaction between astrocytes and microglia plays a vital role in the damage and repair of brain lesions due to traumatic brain injury (TBI). Recent... -
Correction to: SALP, a new single-stranded DNA library preparation method esp...
After publication of the original article [1] the authors noted that the additional files had not been uploaded correctly. -
Gender difference in utilization willingness of institutional care among the ...
Abstract Background Institutional care has become an urgent issue in rural China. Rural single seniors, compared with their counterparts, have lower income and are more... -
s·nr: a visual analytics framework for contextual analyses of private and pub...
Abstract Background Next-Generation Sequencing (NGS) has been widely accepted as an essential tool in molecular biology. Reduced costs and automated analysis pipelines make the... -
Golgi tethering factor golgin-97 suppresses breast cancer cell invasiveness b...
Abstract Background Golgin-97 is a tethering factor in the trans-Golgi network (TGN) and is crucial for vesicular trafficking and maintaining cell polarity. However, the... -
Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
Genome-wide DNA methylation at birth in relation to in utero arsenic exposure...
Abstract Background In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life.... -
Molecular characteristics of Staphylococcus aureus isolates from food surveil...
Abstract Background Staphylococcal food poisoning (SFP) is one of the most common food-borne diseases in the world. Pulsed-field gel electrophoresis (PFGE), multilocus sequence... -
Assessment of eating disorders with the diabetes eating problems survey – rev...
Abstract Background The purpose of the study was to evaluate in a sample of insulin-treated diabetic patients, with type 1 or type 2 diabetes, the psychometric characteristics... -
ISSEC: inferring contacts among protein secondary structure elements using de...
Abstract Background The formation of contacts among protein secondary structure elements (SSEs) is an important step in protein folding as it determines topology of protein... -
Managing or restricting movement? Diverging approaches of African and Europea...
Abstract Though a common EU-African agenda of dealing with migration goes back at least a decade with bilateral, regional and continental approaches, it has gained in visible... -
Self- vs proxy-reported mobility using the mobility assessment tool-short for...
Abstract Background Mobility is fundamental to maintenance of an independent lifestyle and can predict clinical outcomes after health events among older individuals. However,... -
Patternable particle microarray utilizing controllable particle delivery
Abstract In this study, we demonstrate an on-demand delivering and sequential arraying of single microparticles utilizing multiple pneumatic pressure-driven elastomer valves and... -
Retrospective analysis in oculocutaneous albinism patients for the 2.7 kb del...
Abstract Background Oculocutaneous albinism (OCA) is an autosomal recessive disorder. A significant portion of OCA patients has been found with a single pathogenic variant... -
Bone marrow failure may be caused by chromosome anomalies exerting effects on...
Abstract Background The majority of the cases of bone marrow failure syndromes/aplastic anaemias (BMFS/AA) are non-hereditary and considered idiopathic (80â 85%). The... -
Next-generation sequencing analysis of receptor-type tyrosine kinase genes in...
Abstract Background Improvement in genetic characterization of Colon Cancer (CC) patients is required to propose new potential targets, since surgical resection coupled to... -
HN1 contributes to migration, invasion, and tumorigenesis of breast cancer by...
Abstract Background Hematological and neurological expressed 1 (HN1) is upregulated in many tumors, but the role of HN1 in breast cancer progression and its regulatory mechanism... -
Cherenkov luminescence imaging is a fast and relevant preclinical tool to ass...
Abstract Purpose Molecular imaging techniques visualise biomarkers for both drug development and personalised medicine. In this field, Cherenkov luminescence imaging (CLI) seems... -
Scl-Ab reverts pro-osteoclastogenic signalling and resorption in estrogen def...
Abstract Background Neutralising antibodies to sclerostin (Scl-Ab) have shown significant potential to induce bone formation and decrease bone resorption, increase strength and... -
New-onset non-infectious pulmonary manifestations among patients with systemi...
Abstract Objective The objective was to estimate the incidence of lung disease among patients with systemic lupus erythematosus (SLE). Methods Using Swedish register data, we...