1,177 items found

Types: other Tags: Molecular Biology Biochemistry

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    Multiwavelength parallel phase-shifting digital holography using angular mult...

    We propose a single-shot digital holography for recording multiwavelength and complex amplitude information by using a single monochromatic image sensor. The zeroth-order wave...
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    Adolescent BMI and early-onset type 2 diabetes among Ethiopian immigrants and...

    Abstract Background We assessed in a nationwide cohort the association between adolescent BMI and early-onset (
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    Bioavailability of subcutaneous and intramuscular administrated buprenorphine...

    Abstract Background Buprenorphine is one of the most used analgesics for postoperative pain in rabbits. The recommended dose in rabbits (0.01–0.05 mg/kg) is the same for...
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    Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammatio...

    Abstract Background The interaction between astrocytes and microglia plays a vital role in the damage and repair of brain lesions due to traumatic brain injury (TBI). Recent...
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    Correction to: SALP, a new single-stranded DNA library preparation method esp...

    After publication of the original article [1] the authors noted that the additional files had not been uploaded correctly.
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    Condition-specific promoter activities in Saccharomyces cerevisiae

    Abstract Background Saccharomyces cerevisiae is widely studied for production of biofuels and biochemicals. To improve production efficiency under industrially relevant...
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    Golgi tethering factor golgin-97 suppresses breast cancer cell invasiveness b...

    Abstract Background Golgin-97 is a tethering factor in the trans-Golgi network (TGN) and is crucial for vesicular trafficking and maintaining cell polarity. However, the...
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    Omalizumab in patients with severe asthma and persistent sputum eosinophilia

    Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who...
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    Genome-wide DNA methylation at birth in relation to in utero arsenic exposure...

    Abstract Background In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life....
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    Novel mutation in the CHST6 gene causes macular corneal dystrophy in a black ...

    Abstract Background Macular corneal dystrophy (MCD) is a rare autosomal recessive disorder that is characterized by progressive corneal opacity that starts in early childhood...
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    ISSEC: inferring contacts among protein secondary structure elements using de...

    Abstract Background The formation of contacts among protein secondary structure elements (SSEs) is an important step in protein folding as it determines topology of protein...
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    Regulation of STEP61 and tyrosine-phosphorylation of NMDA and AMPA receptors ...

    Abstract Background Sustained changes in network activity cause homeostatic synaptic plasticity in part by altering the postsynaptic accumulation of N-methyl-D-aspartate...
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    CRISPR/dCas9-mediated transcriptional improvement of the biosynthetic gene cl...

    Abstract Background The CRISPR/dCas9 system is a powerful tool to activate the transcription of target genes in eukaryotic or prokaryotic cells, but lacks assays in complex...
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    Efficient production of extracellular pullulanase in Bacillus subtilis ATCC60...

    Abstract Background Bacillus subtilis has been widely used as a host for heterologous protein expression in food industry. B. subtilis ATCC6051 is an alternative expression host...
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    Next-generation sequencing analysis of receptor-type tyrosine kinase genes in...

    Abstract Background Improvement in genetic characterization of Colon Cancer (CC) patients is required to propose new potential targets, since surgical resection coupled to...
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    Sex hormones affect endothelial lipase-mediated lipid metabolism and atherosc...

    Abstract Background Endothelial lipase (EL) plays an important role in lipoprotein metabolism and atherosclerosis. To study the functional roles of EL, we recently generated...
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    HN1 contributes to migration, invasion, and tumorigenesis of breast cancer by...

    Abstract Background Hematological and neurological expressed 1 (HN1) is upregulated in many tumors, but the role of HN1 in breast cancer progression and its regulatory mechanism...
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    Cherenkov luminescence imaging is a fast and relevant preclinical tool to ass...

    Abstract Purpose Molecular imaging techniques visualise biomarkers for both drug development and personalised medicine. In this field, Cherenkov luminescence imaging (CLI) seems...
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    Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen...

    Abstract Background Nuclear receptor family member, Estrogen related receptor β, and the Hedgehog signal transduction pathway are both reported to relate to tumorigenesis and...
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    Molecular characterization of flavanone 3-hydroxylase gene and flavonoid accu...

    Abstract Background Among secondary metabolites, flavonoids are particularly crucial for plant growth, development, and reproduction, as well as beneficial for maintenance of...