4 items found

Groups: Metadata-only Access Tags: Molecular Biology

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    Maternal eNOS Deficiency Determines a Fatty Liver Phenotype of the Offspring ...

    Maternal environmental factors can impact the phenotype of the offspring via the induction of epigenetic adaptive mechanisms. The advanced fetal programming hypothesis proposes...
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    SRF modulates seizure occurrence, activity induced gene transcription and hip...

    Abstract A hallmark of temporal lobe epilepsy (TLE) is hippocampal neuronal demise and aberrant mossy fiber sprouting. In addition, unrestrained neuronal activity in TLE...
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    CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development

    Abstract Background Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe...
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    A randomised, double-blind clinical phase II trial of the efficacy, safety, t...

    Abstract Background The clinical development of a single encounter treatment for uncomplicated malaria has the potential to significantly improve the effectiveness of...