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Single nucleotide polymorphisms in apoptosis pathway are associated with resp...
Abstract Background The mechanism of action of imatinib is known to involve the Fas-mediated apoptosis pathway. Consequently inter-individual variations in this apoptosis... -
Anthocyanins abrogate glutamate-induced AMPK activation, oxidative stress, ne...
Abstract Background Glutamate-induced excitotoxicity, oxidative damage, and neuroinflammation are believed to play an important role in the development of a number of CNS... -
Additional file 2: of CpG site methylation in CRYAA promoter affect transcrip...
Row data of qRT-PCR for CRYAA after Zebularine treatment, Experiment 1, Part 2. It is the rata data of part 2 of the first experiment described above. (XLS 2440Â kb) -
Leveraging 3D chemical similarity, target and phenotypic data in the identifi...
Abstract Background Drug-target identification is crucial to discover novel applications for existing drugs and provide more insights about mechanisms of biological actions,... -
r37980778c78--debb52f309907ba051af6bc487a8be55
(A) Choice between water sweetened with saccharin and cocaine. The horizontal dashed line at 0 indicates the indifference level. Values above 0 indicate a preference for sweet... -
Additional file 2: of Cigarette smoke alters the ability of human dendritic c...
S.pneumoniae-induced CXCL8 secretion by PBMC from non-smoker healthy subjects (n = 14), smokers without COPD (n = 13) and COPD patients (n = 9). Supernatants were collected... -
Additional file 1: of Changes in circulating lipids level over time after acq...
Figure S1. Changes in body mass index over time in HCV+ and HCV- persons.(DOC 49 kb) -
Additional file 1: of Cigarette smoke alters the ability of human dendritic c...
Primer sequences. (DOCX 35 kb) -
Genome-wide recruitment profiling of transcription factor Crz1 in response to...
Exposure of the budding Saccharomyces cerevisiae to an alkaline environment produces a robust transcriptional response involving hundreds of genes. Part of this response is... -
Co-expression of ghrelin and ENaC subunits in fungiform papillae of WT (A,B) ...
(A) ghrelin and ENaCα are co-localized in a subset of ghrelin-positive cells in WT mice. Arrow, cell expressing both. (B) ghrelin and ENaCγ are co-localized in a subset of... -
Additional file 2: Table S2. of Identification and annotation of conserved pr...
Table S2A â Locations of FANTOM5 human promoters mapped to the pig genome. Table contains the following columns (left to right): FANTOM5 human promoter ID, Ensembl gene ID... -
Assignment of sigma factors of RNA polymerase to promoters in Corynebacterium...
Abstract Corynebacterium glutamicum is an important industrial producer of various amino acids and other metabolites. The C. glutamicum genome encodes seven sigma subunits... -
r37980778c78--ae4aee7484bbcc34ecdfe69868502683
The 5-hydroxytryptamine 2A (5-HT2A) receptor is a member of the G protein-coupled receptor superfamily (GPCR) and plays a key role in transducing a variety of cellular signals... -
Validation of T-Track® CMV to assess the functionality of cytomegalovirus-rea...
Abstract Background Uncontrolled cytomegalovirus (CMV) replication in immunocompromised solid-organ transplant recipients is a clinically relevant issue and an indication of... -
Additional file 1 of Associations between bride price stress and intimate par...
A: Association between poverty-related stress and bride price stress. (DOCX 13Â kb) -
Additional file 2: Figure S1. of Transcriptome analysis of bronchoalveolar la...
The levels of immunoglobulins in the peripheral blood of MPP patients. A. The levels of IgG in each patients. Normal range of 5.09–14.17 g/L is shown as dotted lines. B. The... -
Alteration of G<sub>M2</sub> ganglioside catabolism in the brain tissues of <...
Histograms show the ratio of GM2 and GM1 gangliosides as measured by TLC in the extracts of brain tissues from wild-type (WT); Neu4−/−,Hexa−/− and Neu4−/−;Hexa−/− mice. Values... -
Additional file 7: Figure S3. of Predominant expression of Alzheimer’s diseas...
Identification of human brain BIN1 isoforms. (A) Schematic illustration of the exon structure of BIN1 and possible alternate splicing. (B) Analysis of human brain RT-PCR... -
Hsa-let-7c-5p augments enterovirus 71 replication through viral subversion of...
Abstract Background Human enterovirus 71 (EV71) causes severe hand, foot and mouse disease, accompanied by neurological complications. During the interaction between EV71 and...
