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Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
Risk factors for poor asthma control and impaired quality of life in a Caribb...
Asthma, a major cause of disability and reduced quality of life, has a high global prevalence and burden of death. Despite the propitious guidelines, a substantial portion of... -
TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTOR...
Macroautophagy/autophagy is an evolutionarily conserved process that involves the selective degradation of cytoplasmic components within lysosomes in response to starvation.... -
PSA testing patterns in a large Swedish cohort before the implementation of o...
Organized PSA testing for asymptomatic men aged 50–74 years will be implemented in Sweden to reduce opportunistic testing in groups who will not benefit. The aim of this study... -
SUMO conjugation regulates immune signalling
Post-translational modifications (PTMs) are critical drivers and attenuators for proteins that regulate immune signalling cascades in host defence. In this review, we explore... -
The comparison between pulmonary rehabilitation with music therapy and pulmon...
Much emphasis is being placed on the role of music therapy as an easy-to-use, noninvasive and relatively cheap method of asthma treatment. The objective of this interventional... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
dedup_wf_001--5101a4e2d80df72a31b34d26c9459e57
A coke produced using a custom-built sole-heated oven and a coke prepared in a pilot-scale oven from a matched coal, were compared using a range of analytical techniques. The... -
Ceric ammonium nitrate/acetic anhydride: A tunable system for the O-acetylati...
Esterification of a wide range of partially protected carbohydrate derivatives was achieved using acetic anhydride and a catalytic amount of ceric ammonium nitrate (CAN).... -
S100A9/CD163 Expression in Circulating Classical Monocytes in Chronic Obstruc...
Although many studies have characterized polarity of macrophages in chronic obstructive pulmonary disease (COPD), limited information is available regarding cellular phenotypes... -
Effect of recombinant human granulocyte colony-stimulating factor on lymphocy...
Effect of recombinant human granulocyte colony-stimulating factor on lymphocyte subsets in patients with COVID-19 -
dedup_wf_001--53585fd2ae74e46f2b28de670d1bd787
This paper provides insights into trademark activity at the regional level via two objectives. First, it examines the relationship between technological capabilities and new... -
Methylation Status of VDR Gene and its Association with Vitamin D Status and ...
Deficiency in circulatory vitamin D level and vitamin D receptor DNA methylation could be associated with weakened innate immune response and increased susceptibility to... -
Detecting asthma exacerbations using daily home monitoring and machine learning
Objective: Acute exacerbations contribute significantly to the morbidity of asthma. Recent studies have shown that early detection and treatment of asthma exacerbations leads to... -
Determination of phthalate esters in breast milk before and after frozen stor...
This study describes the migration of 20 phthalates from breast milk storage bags to breast milk after storage frozen for 1 to 6 months. Analysis of the investigated phthalates... -
The New Zealand white rabbit animal model of acute radiation syndrome: hemato...
Animal models that accurately reflect human responses to radiation injury are needed for advanced mechanistic investigation and development of effective therapeutics. The rabbit... -
Fractional Exhaled Nitric Oxide as an Inflammatory Biomarker in Chronic Obstr...
We studied whether fractional exhaled nitric oxide (F ENO) can differentiate chronic obstructive pulmonary disease (COPD) with concurrent diagnosis of asthma from COPD-only as... -
miR-296-5p inhibits IL-1β-induced apoptosis and cartilage degradation in huma...
Osteoarthritis (OA) is characterized by apoptosis of chondrocytes and an imbalance of extracellular matrix (ECM) synthesis and catabolism. Emerging evidence has demonstrated... -
RNA secondary structure at the transcription start site influences EBOV trans...
Ebola virus (EBOV) RNA has the potential to form hairpin structures at the transcription start sequence (TSS) and reinitiation sites of internal genes, both on the genomic and... -
Long-read sequencing uncovers a complex transcriptome topology in varicella z...
Abstract Background Varicella zoster virus (VZV) is a human pathogenic alphaherpesvirus harboring a relatively large DNA molecule. The VZV transcriptome has already been...
