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Oxidative stress and premature senescence in corneal endothelium following pe...
Abstract Background The purpose of this study was to address the question of how the premature senescence process may affect corneal endothelium after penetrating keratoplasty,... -
Time to death and risk factors among tuberculosis patients in Northern Ethiopia
Abstract Objective The main objective of this study was to assess time to death and associated risk factors among tuberculosis (TB) patients. Results A total of 769 TB patients... -
Effects of cyanobacterial toxins on the human gastrointestinal tract and the ...
Abstract Background Cyanobacterial blooms occur with increasing frequency in freshwater ecosystems, posing a hazard to human and environmental health. Exposure of human to... -
Incidence and impact on outcomes of acute kidney injury after a stroke: a sys...
Abstract Background Patients with chronic kidney disease have worse outcomes after stroke. However, the burden of acute kidney injury after stroke has not been extensively... -
Genetic tool for fate mapping of Oct4 (Pou5f1)-expressing cells and their pro...
Abstract Background Methods based on site-specific recombinases are widely used in studying gene activities in vivo and in vitro. In these studies, constitutively active or... -
Avian influenza A (H5N1) outbreaks in different poultry farm types in Egypt: ...
Abstract Background The Avian Influenza A (H5N1) virus is endemic in poultry in Egypt. The winter of 2014/2015 was particularly worrying as new clusters of HPAI A (H5N1) virus... -
Adherence to guidelines across different specialties to prevent infections in...
Abstract Background Substantial numbers of patients are now receiving either immunosuppressive therapies or chemotherapy. There are significant risks in such patients of... -
Efficacy, safety and effectiveness of licensed rotavirus vaccines: a systemat...
Abstract Background RotaTeq™ (RV5; Merck & Co. Inc., USA) and Rotarix™ (RV1, GlaxoSmithKline, Belgium) vaccines, developed to prevent rotavirus diarrhea in children under... -
Boron-deficiency-responsive microRNAs and their targets in Citrus sinensis le...
Abstract Background MicroRNAs play important roles in the adaptive responses of plants to nutrient deficiencies. Most research, however, has focused on nitrogen (N), phosphorus... -
Serum amyloid A primes microglia for ATP-dependent interleukin-1β release
Abstract Background Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A... -
A meta-analysis of depressive symptoms among Ethiopian prisoners and a narrat...
Abstract Background The burden of depression in prisoners is increasing and factors such as co-existence of medical illness, lack of social support and longer duration of... -
Effects of very early start of norepinephrine in patients with septic shock: ...
Abstract Background Optimal timing for the start of vasopressors (VP) in septic shock has not been widely studied since it is assumed that fluids must be administered in... -
Downstream consequences of diagnostic error in pediatric anaphylaxis
Abstract Background Pediatric anaphylaxis is commonly misdiagnosed in the Emergency Department (ED). We aimed to determine the impact of inaccurate diagnosis on the management... -
Helios + Regulatory T cell frequencies are correlated with control of viral r...
Abstract Background The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation.... -
Treating loss-to-follow-up as a missing data problem: a case study using a lo...
Abstract Background HIV programs are often assessed by the proportion of patients who are alive and retained in care; however some patients are categorized as lost to follow-up... -
BCG vaccination in southern rural Mozambique: an overview of coverage and its...
Abstract Background Over the past four decades, the World Health Organization established the Expanded Programme on Immunization (EPI) to foster universal access to all relevant... -
Probiotics may not prevent the deterioration of necrotizing enterocolitis fro...
Abstract Background Probiotic therapy can reduce the incidence of NEC. Therapeutic use of probiotics after NEC diagnosis reduces the severity of NEC in preterm infants or... -
Bone marrow failure may be caused by chromosome anomalies exerting effects on...
Abstract Background The majority of the cases of bone marrow failure syndromes/aplastic anaemias (BMFS/AA) are non-hereditary and considered idiopathic (80â 85%). The... -
Increased calcium intake is associated lower serum 25-hydroxyvitamin D levels...
Abstract Background There are indications that an increased intake of calcium has a vitamin D sparing effect, which might be explained by a decreased catabolism of... -
Transcriptionally induced enhancers in the macrophage immune response to Myco...
Abstract Background Tuberculosis is a life-threatening infectious disease caused by Mycobacterium tuberculosis (M.tb). M.tb subverts host immune responses to build a favourable...
