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18F-VC701-PET and MRI in the in vivo neuroinflammation assessment of a mouse ...
Abstract Background Positron emission tomography (PET) using translocator protein (TSPO) ligands has been used to detect neuroinflammatory processes in neurological disorders,... -
Perioperative cerebrospinal fluid and plasma inflammatory markers after ortho...
Abstract Background Postoperative delirium is prevalent in older patients and associated with worse outcomes. Recent data in animal studies demonstrate increases in inflammatory... -
Oxidative stress and premature senescence in corneal endothelium following pe...
Abstract Background The purpose of this study was to address the question of how the premature senescence process may affect corneal endothelium after penetrating keratoplasty,... -
Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammatio...
Abstract Background The interaction between astrocytes and microglia plays a vital role in the damage and repair of brain lesions due to traumatic brain injury (TBI). Recent... -
Optical coherence tomography in myelin-oligodendrocyte-glycoprotein antibody-...
Abstract Background Serum antibodies against myelin-oligodendrocyte-glycoprotein (MOG-IgG) are detectable in a proportion of patients with acute or relapsing neuroinflammation.... -
Dietary intake of total, animal and plant proteins and the risk of coronary h...
Previous findings assessing the association between long-term protein intake and cardiovascular diseases (CVDs) are inconsistent. This study aimed to summarize previous... -
Involvement of ABC-transporters and acyltransferase 1 in intracellular choles...
Abstract Background Understanding pathogenic mechanisms is imperative for developing novel treatment to the tuberculosis, an important public health burden worldwide. Recent... -
Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
Effects of very early start of norepinephrine in patients with septic shock: ...
Abstract Background Optimal timing for the start of vasopressors (VP) in septic shock has not been widely studied since it is assumed that fluids must be administered in... -
Downstream consequences of diagnostic error in pediatric anaphylaxis
Abstract Background Pediatric anaphylaxis is commonly misdiagnosed in the Emergency Department (ED). We aimed to determine the impact of inaccurate diagnosis on the management... -
Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-indu...
Abstract Background Although allergic asthma is a complex area with many interacting factors involved, the ‘hygiene hypothesis’ proposes that a lack of exposure to infection... -
Excessive carbohydrate consumption and body mass index: the risk factors for ...
Abstract Background Prader-Willi syndrome (PWS) is commonly associated with severe obesity and type 2 diabetes mellitus (T2DM) and is caused by excessive eating. Only very few... -
Gout and the risk of Parkinson’s disease in older adults: a study of U.S. Med...
Abstract Background In the presence of limited available data, our objective was to assess the association of gout with the risk of incident Parkinson’s disease (PD) in adults... -
Serum progesterone distribution in normal pregnancies compared to pregnancies...
Abstract Background Progesterone is a critical hormone in early pregnancy. A low level of serum progesterone is associated with threatened miscarriage. We aim to establish the... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Nanomedicine-driven neuropathic pain relief in a rat model is associated with...
Abstract We explored the immune neuropathology underlying multi-day relief from neuropathic pain in a rat model initiated at the sciatic nerve, by using a nanoemulsion-based... -
Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen...
Abstract Background Nuclear receptor family member, Estrogen related receptor β, and the Hedgehog signal transduction pathway are both reported to relate to tumorigenesis and... -
Real-time color electroholography using multiple graphics processing units an...
We succeeded in developing a prototype three-dimensional (3-D) color television system by holography using three graphics processing units and three liquid-crystal display... -
Incidence and risk factors for food hypersensitivity in UK infants: results f...
Abstract Background The prevalence of food hypersensitivity in the UK is still largely open to debate. Additionally its pathogenesis is also unclear although it is known that... -
Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate...
Abstract Background Dexketoprofen trometamol plus tramadol hydrochloride is a new oral combination of two analgesics, which have different mechanisms of action for the treatment...
