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IL-6-activated Stat3 binds to the ROR1 promoter and activates transcription i...
A. ROR1 promoter biotinylated DNA probe binds to nuclear protein of unstimulated or IL-6-stimulated MM1 cells. The addition of an unlabeled (cold) probe attenuated the binding... -
Characteristics of patients included in the study.
CRC, colorectal cancer; NA, not applied. 1Qualitative variables were compared by the Fisher's exact test; continuous variables were compared by the Mann-Whitney U's... -
r37980778c78--1ad25205d128401f96981bc7f01b8739
A. A 67% infection efficiency of retroviral STAT3-shRNA into CLL cells from a patient was obtained. B. qRT-PCR of these CLL cells demonstrates that STAT3-shRNA downregulated... -
Insights from the ganglionic acetylcholine receptor autoantibodies in patient...
Objective: It is not known whether autonomic neuropathy is a feature of Sjögren’s syndrome (SS) or whether it is related to circulating antiganglionic acetylcholine receptor... -
Model parameters.
aSpecified with reference to Cook [30] and Waage et al. [36] using distributions defined in Biosecurity Australia [31]; b Derived from Sapoukhina et al. [37]; c ABS [6], Note... -
Additional file 2: of The impairment of small nerve fibers in severe sepsis a...
Nerve conduction studies. Amplitudes of compound potentials in motor and sensory nerves are considerably decreased, and conduction velocity is marginally impaired. Note that... -
Increased expression of dedicator-cytokinesis-10, caspase-2 and Synaptotagmin...
Abstract Background We aim to identify differentially expressed genes (DEGs) and its pathways associated with clinical activity of relapsing–remitting Multiple Sclerosis (RRMS).... -
Additional file 1: of Sociodemographic, clinical, and psychosocial factors as...
This is a cleaned comma delimited (*.csv) dataset titled â Patients sociodemographic, clinical, psychosocial, and depressive symptom raw dataâ . It comprises patientsâ... -
A survey of thrombosis experts evaluating practices and opinions regarding ve...
Abstract Background Patients undergoing major abdominal surgery are at high risk for developing venous thromboembolism in the post-operative period. Current evidence-based... -
Characteristics of study subjects.
JA-1, first-generation Japanese-Americans; JA-2, second- or later-generation Japanese-Americans; BMI, body mass index; BP, blood pressure; 2-h, two-hour post-load; HOMA-IR,... -
Primers used in this study.
a Liu et al., 2011 [19]. b Ji et al., 2007 [20]. c Wei et al., 2010 [21]. d Noteborn et al., 2013 [22]. *Positions correspond to: IBDV (JQ684022), IBV (KJ425500), AEV... -
Additional file 2: Figure S1. of Development of an integrated approach for co...
Resazurin reduction by J774A.1 (A) and A549 (B) cells exposed to particles. Average fold-effect (FE) over control ± standard error values are shown (n = 5). ATP content of... -
Characteristics of the study population.
SD = standard deviation; BMI = body mass index; BFP = Body fat percentage measured with bioelectrical impedance [24]; WHR = waist-hip ratio; HGS = handgrip strength, the highest... -
Patient Characteristics.
Abbreviations: AML, acute myeloid leukemia; sAML, secondary AML; ALL, acute lymphoblastic leukemia; PMF, primary myelofibrosis; CLL: chronic lymphoblastic leukemia; SAA, severe... -
r37980778c78--593ba6ca465f237fa77c34c92fac6627
A. Western immunoblotting of unstimulated CLL cells from 7 different patients shows constitutive expression of phosphoserine-Stat3 and both the 105- and 130-Kd variants of the... -
Data collection and refinement statistics.
1Statistics for data from the highest-resolution shell are shown in parentheses. 2 R sym =(ΣΣ|Ihkl−〈I〉|)/(ΣIhkl), where the average intensity <I> is taken... -
CLL-cell constitutively activated Stat3 binds the ROR1 promoter at the previo...
A. EMSA, performed using cells of CLL patients 8 and 9, demonstrates that CLL-cell nuclear protein binds the ROR1 biotinylated (labeled)-DNA probe. The cold (unlabeled) probe... -
Sequence of the 5′-flanking region of the human ROR1 promoter.
Underlined are the primers used to generate ROR1 promoter fragments. The putative Stat3 binding sites are shown in red. Gray denotes the exon region and ATG is the starting codon. -
Characterization and pathogenesis of aerosolized eastern equine encephalitis ...
Abstract Background Licensed antiviral therapeutics and vaccines to protect against eastern equine encephalitis virus (EEEV) in humans currently do not exist. Animal models that... -
Baseline characteristics of the study population.
Values are expressed as medians (range or percentage). * Hypertension: Yes = systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg, or treated with...
