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Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
Burden of disease and costs associated with type 2 diabetes in emerging and e...
To estimate the clinical and economic burden of type 2 diabetes (T2D) in established (EST) and emerging markets (EMG). Three systematic literature reviews were conducted in... -
Cost per responder analysis of guselkumab versus targeted therapies in the tr...
BACKGROUND The fully human monoclonal antibody guselkumab is an effective treatment option for patients with moderate to severe psoriasis. OBJECTIVE The objective of this study... -
dedup_wf_001--213f0b34bc1cd5e5b423276cd6b90694
To assess the real-world effectiveness of golimumab in Japanese patients with rheumatoid arthritis who had previously received first-line biologic therapy. A post-hoc analysis... -
Association of tenofovir disoproxil fumarate exposure with chronic kidney dis...
Tenofovir disoproxil fumarate (TDF)-based regimens have been associated with impaired kidney function and loss of bone mineral density among patients living with HIV (PLWH). We... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
dedup_wf_001--5101a4e2d80df72a31b34d26c9459e57
A coke produced using a custom-built sole-heated oven and a coke prepared in a pilot-scale oven from a matched coal, were compared using a range of analytical techniques. The... -
dedup_wf_001--56eae353b03f1ff5174164ffccd7434b
Vaginal delivery is a well‐known risk factor for pelvic floor muscle (PFM) injuries, mainly when associated to prolonged labor, instrumental birth and perineal trauma such as... -
dedup_wf_001--cb0d03892af33ee8063f732ae96b1c08
We show how a factor analysis model can be fitted to nominal data using the computer program Mplus. The model is akin to multinomial logistic regression with unobserved... -
Genetic factors in anthracycline-induced cardiotoxicity in patients treated f...
Cardiovascular diseases are the main cause of treatment-related morbidity and mortality in childhood cancer patients. Anthracyclines, one of the most common chemotherapeutic... -
The Cold War as an Aesthetic Phenomenon: An Afterthought on Boris Groys
The Cold War as an Aesthetic Phenomenon: An Afterthought on Boris Groys -
dedup_wf_001--59716430bf39cad654eeab4b69760468
A physiologically based pharmacokinetic (PBPK) model for di-isononyl phthalate (DiNP) was developed by adapting the existing models for di(2-ethylhexyl) phthalate (DEHP) and... -
dedup_wf_001--2a0036ce8c94364642f4ee2734a44384
Dravet syndrome (DS), a prototypic developmental and genetic epileptic encephalopathy (DEE), is characterized by an early onset of treatment-refractory seizures, together with... -
Responsible innovation in school design – a systematic review
This paper considers Responsible Innovation (RI) in relation to the design, construction and use of new schools. Drawing on empirical findings from recent international research... -
Effect of Diamond-like Carbon Coating on Preventing the Ingress of Hydrogen i...
The failure of moving mechanical components is often accompanied by hydrogen embrittlement caused by hydrogen diffusion in steel. One considerable mechanism for hydrogen... -
dedup_wf_001--a66673170c588b96a033e52307ed883a
Lavandula angustifolia Mill. (lavender) and Origanum heracleoticum L. (greek oregano) are aromatic plants used in traditional medicine for relief of convulsion, anxiety,...
