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Male-benefit sexually antagonistic genotypes show elevated vulnerability to i...
Abstract Background There is theoretical and empirical evidence for strong sexual selection in males having positive effects on population viability by serving to purify the... -
Perioperative cerebrospinal fluid and plasma inflammatory markers after ortho...
Abstract Background Postoperative delirium is prevalent in older patients and associated with worse outcomes. Recent data in animal studies demonstrate increases in inflammatory... -
Erratum to: Pain management strategies for neuropathic pain in Fabry disease ...
Erratum to: Pain management strategies for neuropathic pain in Fabry disease - a systematic review -
Acute severe paediatric asthma: study protocol for the development of a core ...
Abstract Background Acute severe childhood asthma is an infrequent, but potentially life-threatening emergency condition. There is a wide range of different approaches to this... -
Genetic tool for fate mapping of Oct4 (Pou5f1)-expressing cells and their pro...
Abstract Background Methods based on site-specific recombinases are widely used in studying gene activities in vivo and in vitro. In these studies, constitutively active or... -
Involvement of ABC-transporters and acyltransferase 1 in intracellular choles...
Abstract Background Understanding pathogenic mechanisms is imperative for developing novel treatment to the tuberculosis, an important public health burden worldwide. Recent... -
Genome-wide DNA methylation at birth in relation to in utero arsenic exposure...
Abstract Background In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life.... -
Molecular characteristics of Staphylococcus aureus isolates from food surveil...
Abstract Background Staphylococcal food poisoning (SFP) is one of the most common food-borne diseases in the world. Pulsed-field gel electrophoresis (PFGE), multilocus sequence... -
Novel mutation in the CHST6 gene causes macular corneal dystrophy in a black ...
Abstract Background Macular corneal dystrophy (MCD) is a rare autosomal recessive disorder that is characterized by progressive corneal opacity that starts in early childhood... -
Factors associated with the development of septic shock in patients with cand...
Abstract Background Almost one third of the patients with candidemia develop septic shock. The understanding why some patients do and others do not develop septic shock is very... -
Pleural effusion from intrathoracic migration of a ventriculo-peritoneal shun...
Abstract Background Pleural effusion is a rare complication of ventriculo-peritoneal (VP) cerebrospinal fluid (CSF) shunting and its diagnosis is difficult in patients with... -
Effects of very early start of norepinephrine in patients with septic shock: ...
Abstract Background Optimal timing for the start of vasopressors (VP) in septic shock has not been widely studied since it is assumed that fluids must be administered in... -
Autonomic nervous system response to remote ischemic conditioning: heart rate...
Abstract Background Remote ischemic conditioning (RIC) is a procedure applied in a limb for triggering endogenous protective pathways in distant organs, namely brain or heart.... -
Helios + Regulatory T cell frequencies are correlated with control of viral r...
Abstract Background The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation.... -
Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-indu...
Abstract Background Although allergic asthma is a complex area with many interacting factors involved, the ‘hygiene hypothesis’ proposes that a lack of exposure to infection... -
Patternable particle microarray utilizing controllable particle delivery
Abstract In this study, we demonstrate an on-demand delivering and sequential arraying of single microparticles utilizing multiple pneumatic pressure-driven elastomer valves and... -
Retrospective analysis in oculocutaneous albinism patients for the 2.7 kb del...
Abstract Background Oculocutaneous albinism (OCA) is an autosomal recessive disorder. A significant portion of OCA patients has been found with a single pathogenic variant... -
Next-generation sequencing analysis of receptor-type tyrosine kinase genes in...
Abstract Background Improvement in genetic characterization of Colon Cancer (CC) patients is required to propose new potential targets, since surgical resection coupled to... -
Using predicate and provenance information from a knowledge graph for drug ef...
Abstract Background Biomedical knowledge graphs have become important tools to computationally analyse the comprehensive body of biomedical knowledge. They represent knowledge... -
Additional file 7: of The prominent alteration in transcriptome and metabolom...
Table S7. The homologous genes between M. bovis BCG and M. tuberculosis H37Rv. (XLS 1840 kb)
