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Context-specific functional module based drug efficacy prediction
Background It is necessary to evaluate the efficacy of individual drugs on patients to realize personalized medicine. Testing drugs on patients in clinical trial is the only way... -
RGmatch: matching genomic regions to proximal genes in omics data integration
© The Author(s). 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License... -
A fast exact sequential algorithm for the partial digest problem
Background Restriction site analysis involves determining the locations of restriction sites after the process of digestion by reconstructing their positions based on the... -
Drug-target interaction prediction via class imbalance-aware ensemble learning
Background Multiple computational methods for predicting drug-target interactions have been developed to facilitate the drug discovery process. These methods use available data... -
Towards a phenome-wide catalog of human clinical traits impacted by genetic a...
Background Racial/ethnic differences for commonly measured clinical variables are well documented, and it has been postulated that population-specific genetic factors may play a... -
SnoReport 2.0: new features and a refined Support Vector Machine to improve s...
Background snoReport uses RNA secondary structure prediction combined with machine learning as the basis to identify the two main classes of small nucleolar RNAs, the box H/ACA... -
A generic schema and data collection forms applicable to diverse entomologica...
Background Standardized schemas, databases, and public data repositories are needed for the studies of malaria vectors that encompass a remarkably diverse array of designs and... -
Tackling the challenges of matching biomedical ontologies
Background Biomedical ontologies pose several challenges to ontology matching due both to the complexity of the biomedical domain and to the characteristics of the ontologies...
