Geographic information has become central for data scientists of many disciplines to put their analyzes into a spatio-temporal perspective. However, just as the volume and...

Peer and panel review are the dominant forms of grant decision-making, despite its serious weaknesses as shown by many studies. This paper contributes to the understanding of...

Background: Identification of biological specimens is a major requirement for a range of applications. Reference-free methods analyse unprocessed sequencing data without relying...

Background The yield obtained from next generation sequencers has increased almost exponentially in recent years, making sample multiplexing common practice. While barcodes...

© The Author(s). 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License...

Background Several tools are available for visualizing genomic data. Some, such as Gbrowse and Jbrowse, are very efficient for small genomic regions, but they are not suitable...

Background Comparative analysis of whole genome sequence data from closely related prokaryotic species or strains is becoming an increasingly important and accessible approach...

Joining element design is mainly a manual task resulting in costly and prolonged development trajectories. Current limited automation solutions support engineers, but still lead...

Background Often researchers are interested in comparing multiple experimental groups (e.g. tumor size) with a reference group (e.g. normal tissue) on the basis of thousands of...

Background Prediction models are used in clinical research to develop rules that can be used to accurately predict the outcome of the patients based on some of their...

Background Phenotypic studies in Triticeae have shown that low temperature-induced protective mechanisms are developmentally regulated and involve dynamic acclimation processes....

International audience; This paper proposes to broaden by more than 10%-compared with the current practice-the set of applications for priority patents, which is used to compute...

Background The Friedman rank sum test is a widely-used nonparametric method in computational biology. In addition to examining the overall null hypothesis of no significant...

Bibliometric analysis techniques are increasingly being used to analyze and evaluate scientific research produced by institutions and grant funding agencies. This article uses...

Background In the context of high-throughput molecular data analysis it is common that the observations included in a dataset form distinct groups; for example, measured at...

Background Data extraction and integration methods are becoming essential to effectively access and take advantage of the huge amounts of heterogeneous genomics and clinical...

Background Targeted next-generation sequencing is playing an increasingly important role in biological research and clinical diagnosis by allowing researchers to sequence high...

Background One of our goals for the echinoderm tree of life project (http://echinotol.org) is to identify orthologs suitable for phylogenetic analysis from next-generation...

Background Restriction site analysis involves determining the locations of restriction sites after the process of digestion by reconstructing their positions based on the...

Background The knowledge base-driven pathway analysis is becoming the first choice for many investigators, in that it not only can reduce the complexity of functional analysis...