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Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
Abstract Background CpG islands (CGIs) are interspersed DNA sequences that have unusually high CpG ratios and GC contents. CGIs are typically located in the promoter of... -
Additional file 1: of Are digital interventions for smoking cessation in preg...
PRISMA-P checklist. This checklist includes a list of recommended items to include in a systematic review protocol and where these can be found in this protocol. (DOC 82.5 kb) -
How Robust Are Multirater Interrater Reliability Indices to Changes in Freque...
Interrater reliability studies are used in a diverse set of fields. Often, these investigations involve three or more raters, and thus, require the use of indices such as... -
Additional file 3: of Drug seller adherence to clinical protocols with integr...
The sick child job aid 2. This is a visual aid that contains the iCCM treatment algorithm. It is printed in A3 size and displayed in the drug shop for easy reference when... -
Additional file 8 of Drug combinatorics and side effect estimation on the sig...
Text file containing all drug pairs having side effect scores b i (j)=b j (i)=0. (TXT 44 kb) -
Infectious tenosynovitis with bloodstream infection caused by Erysipelothrix ...
Abstract Background Erysipelothrix rhusiopathiae is an established animal pathogen, which may cause infections in humans. It is a gram-positive rod and found in the tonsils or... -
Effect of cigarette smoke on monocyte procoagulant activity: Focus on platele...
Cigarette smoke (CS) activates platelets, promotes vascular dysfunction, and enhances Tissue Factor (TF) expression in blood monocytes favoring pro-thrombotic states.... -
Additional file 3: of The response to receiving phenotypic and genetic corona...
Baseline information of the participant in the qualitative study. (DOCX 14 kb) -
The impact of onabotulinumtoxinA on severe headache days: PREEMPT 56-week poo...
Abstract Background OnabotulinumtoxinA has been shown to reduce headache-days among patients with chronic migraine (CM). The objective of this analysis was to determine whether... -
The efficacy of varenicline in achieving abstinence among waterpipe tobacco s...
Abstract Background Waterpipe tobacco smoking has increased among youth across the globe including in the US, and it continues as a common and traditional form of smoking... -
Effectiveness of the addition of therapeutic alliance with minimal interventi...
Abstract Background The stratified model of care has been an effective approach for the treatment of low back pain. However, the treatment of patients with low risk of... -
Additional file 2: of Drug voyager: a computational platform for exploring un...
Predicted drug indications. The list of 1,816 novel drug indications spanning 47 drugs and 122 diseases. (XLSX 54 kb) -
Additional file 2: Table S2. of Pirfenidone attenuates bleomycin-induced pulm...
Original data of RT-PCR in animal experiment. (XLS 43 kb) -
Postural effects on intraocular pressure and ocular perfusion pressure in pat...
Abstract Background To investigate postural effects on intraocular pressure (IOP) and ocular perfusion pressure (OPP) in patients with non-arteritic ischemic optic neuropathy... -
Additional file 1: Table S1. of Antidepressant use and cognitive decline in c...
Multi-adjusted associations of baseline antidepressant use with 10-year cognitive changes in participants without past major depressive episode. Table S2. Multi-adjusted... -
Helveticoside is a biologically active component of the seed extract of Descu...
Abstract Background Although the pharmacological activities of the seed extract of Descurainia sophia have been proven to be useful against cough, asthma, and edema, the... -
Antibiotic prophylaxis is not indicated prior to dental procedures for preven...
Background and purpose — To minimize the risk of hematogenous periprosthetic joint infection (HPJI), international and Dutch guidelines recommended antibiotic prophylaxis prior... -
TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infecti...
Abstract Background Monocytes, the primary myeloid cell-type in peripheral blood, are resistant to HIV-1 infection as a result of the lentiviral restriction factor SAMHD1.... -
Characterization and pathogenesis of aerosolized eastern equine encephalitis ...
Abstract Background Licensed antiviral therapeutics and vaccines to protect against eastern equine encephalitis virus (EEEV) in humans currently do not exist. Animal models that... -
Additional file 7 of Drug combinatorics and side effect estimation on the sig...
Text file containing all drug pairs having side effect scores b i (j)â Ľ0.5 but 0