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Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
Abstract Background CpG islands (CGIs) are interspersed DNA sequences that have unusually high CpG ratios and GC contents. CGIs are typically located in the promoter of... -
Additional file 4: Online Resource 4. of Six-month quality-of-life and functi...
Barthel index (BI) score at baseline and 6Â months among groups of patients with and without acute respiratory distress syndrome (ARDS): sensitivity analysis with the lowest... -
Additional file 2: Table S2. of Identification and annotation of conserved pr...
Table S2A â Locations of FANTOM5 human promoters mapped to the pig genome. Table contains the following columns (left to right): FANTOM5 human promoter ID, Ensembl gene ID... -
Additional file 6: of Inflammasome and toll-like receptor signaling in human ...
Correlation analyses of monocyte mRNA expression levels and clinical characteristics. Shown are correlation analyses of monocyte mRNA expression levels from patients in the... -
Additional file 5: of Analysis of breast milk fatty acid composition using dr...
Fatty acids (C10:0 – C22:6n-3) from dried milk spots stored in a research-grade freezer (-80C) for 3 years. Error bars represent ± 15 % from baseline values. Fatty acids that... -
Implementation of depression screening in antenatal clinics through tablet co...
Abstract Background Mobile devices may facilitate depression screening in the waiting area of antenatal clinics. This can present implementation challenges, of which we focused... -
Additional file 8 of Drug combinatorics and side effect estimation on the sig...
Text file containing all drug pairs having side effect scores b i (j)=b j (i)=0. (TXT 44 kb) -
Additional file 3: of Analysis of breast milk fatty acid composition using dr...
Fatty acids (C10:0 – C22:6n-3) from dried milk spots stored in a refrigerator (4C) for 4 weeks. Error bars represent ± 15 % from baseline values. Fatty acids that represent <... -
Specificity versus redundancy in the RAP2.4 transcription factor family of Ar...
Abstract Background The Arabidopsis ERFIb / RAP2.4 transcription factor family consists of eight members with highly conserved DNA binding domains. Selected members have been... -
"Hit-and-Run" transcription: de novo transcription initiated by a transient b...
Abstract Background Dynamic transcriptional regulation is critical for an organism’s response to environmental signals and yet remains elusive to capture. Such transcriptional... -
Effect of cigarette smoke on monocyte procoagulant activity: Focus on platele...
Cigarette smoke (CS) activates platelets, promotes vascular dysfunction, and enhances Tissue Factor (TF) expression in blood monocytes favoring pro-thrombotic states.... -
Additional file 4: of Analysis of breast milk fatty acid composition using dr...
Fatty acids (C10:0 – C22:6n-3) from dried milk spots stored in a standard freezer (-20C) for 3 years. Error bars represent ± 15 % from baseline values. Fatty acids that... -
Change in renin, cardiovascular and inflammatory markers over three years in ...
Abstract Background To investigate if percentage change (%∆) in renin over a 3 year follow-up is associated with %∆ in cardiovascular and inflammatory markers in a low renin... -
Characterization of novel Bovine Leukemia Virus (BLV) antisense transcripts b...
Abstract Background Bovine Leukemia Virus (BLV) is a deltaretrovirus closely related to the Human T cell leukemia virus-1 (HTLV-1). Cattle are the natural host of BLV where it... -
Murine versus human apolipoprotein E4: differential facilitation of and co-lo...
Abstract Introduction Amyloid β (Aβ) accumulates in the extracellular space as diffuse and neuritic plaques in Alzheimer’s disease (AD). Aβ also deposits on the walls of... -
A novel description of a syndrome consisting of 7q21.3 deletion including DYN...
Abstract Background Chromosomal region 7q21.3 comprises approximately 5.2 mega base pairs that include genes DLX5/6, SHFM1, and DYNC1I1 associated with split hand/split foot... -
Impact of midfoot and Hindfoot involvement on functional disability in Korean...
Abstract Background Foot involvement in rheumatoid arthritis (RA) patients has been reported to severely affect functional capacity and quality of life. We aimed to determine... -
Characterization and pathogenesis of aerosolized eastern equine encephalitis ...
Abstract Background Licensed antiviral therapeutics and vaccines to protect against eastern equine encephalitis virus (EEEV) in humans currently do not exist. Animal models that... -
Additional file 7 of Drug combinatorics and side effect estimation on the sig...
Text file containing all drug pairs having side effect scores b i (j)â Ľ0.5 but 0 -
Genome-wide mapping of promoter-anchored interactions with close to single-en...
Abstract Although the locations of promoters and enhancers have been identified in several cell types, we still have limited information on their connectivity. We developed...
