1,620 items found

Tags: Cancer Computational Biology Pharmacology

Filter Results
  • dataset

    Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D...

    Many chemotherapeutic drugs cause nucleolar stress and p53-independent pathways mediating the nucleolar stress response are emerging. Here, we demonstrate that ribosomal stress...
  • dataset

    Sitagliptin does not reduce the risk of cardiovascular death or hospitalizati...

    Abstract Background To examine the effects of the DPP-4i sitagliptin on CV outcomes during and after incident MI in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin...
  • dataset

    MOESM6 of Microalgal TAG production strategies: why batch beats repeated-batch

    Additional file 6. Optimized model scenarios and corresponding parameters. Optimized TAG yields on light and TAG contents and corresponding model parameter values at which these...
  • dataset

    Using focused pharmacovigilance for ensuring patient safety against antileish...

    Abstract Background Adverse effects of antileishmanial drugs can affect patients’ quality of life and adherence to therapy for visceral leishmaniasis (VL) and post-kala-azar...
  • dataset

    Additional file 4: Table S2. of Pharmacological regimens for eradication of H...

    Quality assessment of included studies based on revised AMSTAR checklist. (DOCX 17 kb)
  • dataset

    Additional file 18 of Some data quality issues at ClinicalTrials.gov

    Processing of PI names to identify ambiguities—step 2. (XLSX 1406 kb)
  • dataset

    Therapeutic potential of mesenchymal stem cells and their exosomes in severe ...

    Abstract The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19) and the ensuing...
  • dataset

    Visualization 2: Focusing light with orbital angular momentum by circular arr...

    Electric field distribution of the vortex beam measured in time-domain. Originally published in Optics Express on 12 June 2017 (oe-25-12-13728)
  • dataset

    Additional file 1: of Measuring windows of selection for anti-malarial drug t...

    Includes data that support and expand some of the interpretations and conclusions drawn in the main text, but whose inclusion would detract from the main argument.
  • dataset

    Integrating phenotype ontologies with PhenomeNET

    Abstract Background Integration and analysis of phenotype data from humans and model organisms is a key challenge in building our understanding of normal biology and...
  • dataset

    Biofeedback in the prophylactic treatment of medication overuse headache: a p...

    Abstract Background Medication overuse headache (MOH) is a major clinical concern and a common health risk. Recent literature stressed the need to manage chronic headache by...
  • dataset

    Additional file 3: of Alternative DNA secondary structure formation affects R...

    A list of 5959 pausing sites located outside of RefSeq gene bodies. (DAT 234 kb)
  • dataset

    Assessment of overall treatment effect in the presence of inconsistent region...

    The use of multi-regional clinical trials (MRCTs) in clinical developments increased to accelerate patients’ access to new drugs globally. MRCTs inherently assume that the...
  • dataset

    A population-based analysis of the risk of drug interaction between clarithro...

    Abstract Background Clarithromycin, known as a potent inhibitor of the cytochrome P450 isoenzyme CYP3A, may increase the plasma concentration of statins metabolized by this...
  • dataset

    A pharmacist-led medication switch protocol in an academic HIV clinic: patien...

    Abstract Background Tenofovir alafenamide (TAF) is associated with less renal and bone toxicity compared with tenofovir disoproxil (TDF). TAF's recent FDA approval has spurred...
  • dataset

    Ambulatory oxygen in fibrotic lung disease (AmbOx): study protocol for a rand...

    Abstract Background Fibrotic interstitial lung diseases (ILDs) are chronic and often progressive conditions resulting in substantial morbidity and mortality. Shortness of...
  • dataset

    Additional file 3: of Exome analysis of carotid body tumor

    List of evaluated potentially driver mutations and their detailed description. (XLSX 22Â kb)
  • dataset

    A randomized placebo-controlled clinical trial of a multi-strain probiotic fo...

    Abstract Background Accumulating evidence supports the view that an imbalance of gut bacteria contributes to IBS, and that increasing the mass of beneficial species may reduce...