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On the Stereospecific Conversion of Proximally-Oxygenated Trisubstituted Viny...
Allylically oxygenated vinyl α-triphenylstannanes such as 22 can be readily converted into vinyl iodides and thereafter stereodefined trisubstituted alkenes with retention of... -
Ruthenium-Catalyzed [2 + 2] Cycloadditions of Bicyclic Alkenes with Alkynyl P...
Ruthenium-catalyzed [2 + 2] cycloadditions of bicyclic alkenes with alkynyl phosphonates were investigated. The phosphonate moieties were found to be compatible with the... -
Design of Novel Derivatives of Phosphonoformate (Foscarnet) as Prodrugs and A...
Design of Novel Derivatives of Phosphonoformate (Foscarnet) as Prodrugs and Antiviral Agents -
A New Method for the Synthesis of Branched Polysilane Anions
Lithiation by MeLi of three families of branched polysilanes (Me3Si)3Si−X {(1) X = SiMe2H, t-BuMe2Si, SiMe2SiMe3, t-BuSiMe2SiMe2; (2) X = SiMe(SiMe3)2, Si(SiMe3)3,... -
Solid-Phase Synthesis of Bis-2-imidazolidinethiones from Resin-Bound Tripeptides
The exhaustive reduction of resin-bound tripeptides with borane afforded three secondary amines and one primary amine. The treatment of the solid-support polyamines with... -
Diethyl Chlorophosphite: A Versatile Reagent
Diethyl chlorophosphite (DECP) was previously described as a reducing agent for nitro compounds to the corresponding amines (Fischer, B.; Sheihet, L. J. Org. Chem. 1998, 63,... -
From a Biogenetic Scenario to a Synthesis of the ABC Ring of Manzamine A
On the basis of a biogenetic proposal for explaining the biogenesis of manzamine A, the cycloaddition of dihydropyridinium salt 26 with diene derivative 5 leads to adducts 27.... -
Stereospecific Deoxygenation of Phosphine Oxides with Retention of Configurat...
A new protocol for deoxygenation of various phosphine oxides with retention of configuration is described. The advantage of the new method includes milder conditions and... -
Counterattack Mode Differential Acetylative Deprotection of Phenylmethyl Ethe...
A counterattack protocol for differential acetylative cleavage of phenylmethyl ether has been developed. The phenylmethyl moiety is liberated as benzyl bromide that is isolated... -
A New Family of Macrocycles Produced by Sequential Claisen−Schmidt Condensations
Members of a new family of macrocycles have been synthesized in one step, from simple building blocks, by sequential Claisen−Schmidt condensations. -
Photoinduced Electron-Transfer Bicyclopropenyl-benzene Rearrangements of 2,2‘...
The 9,10-dicyanoanthracene-sensitized photoreaction of 1-methyl- and 1,1‘-dimethyl-2,2‘,3,3‘-tetraphenylbicyclopropenyl gives the corresponding benzene and Dewar benzene... -
Synthesis of (−)-Sedinine by Allene Cyclization and Iminium Ion Chemistry
A synthesis of the sedum alkaloid sedinine has been achieved employing silver(I)-catalyzed allenic hydroxylamine cyclization and ring-closing metathesis to form a bicyclic... -
An Efficient C−H Oxidation Protocol for α-Hydroxylation of Cyclic Steroidal E...
Various C-16 hydroxy steroids have been prepared with the aid of CrO3/Bu4NIO4. Out of the two possible reaction courses, transition state B is favored because of less steric... -
Conversion of Weinreb Amides into Benzene Rings Incorporating the Amide Carbo...
Esters, acids and acid chlorides can be converted via the intermediacy of their corresponding Weinreb amides into benzene derivatives that incorporate the original carbonyl... -
Chirally Modified Zeolites as Reaction Media: Photochemistry of an Achiral T...
Zeolites modified with chiral inductors serve as media for performing chiral induction during photochemical reactions of organic molecules. The photochemical behavior of achiral... -
Antiaromaticity in Distal Bisfluorenyl Dications Separated by Multiple Discre...
The effect of spacers on the antiaromaticity of bisfluorenyl dications was examined. For systems such as 4a−c in which extensive delocalization of the positive charge through... -
Nucleophilic Epoxidation of γ-Hydroxyvinyl Sulfoxide Derivatives.
The nucleophilic epoxidation of simple (γ-silyloxy)vinyl sulfoxides takes place with complete stereocontrol and high yields. For substrates bearing an additional substituent at... -
Anion−π Interactions in Four-Membered Rings
In this study, the importance of anion−π interactions in four-membered rings has been evidenced. Two kinds of rings have been found to be suitable for participation in anion−π... -
Design of Biocompatible Dendrimers with Environment Sensitivity
Design of Biocompatible Dendrimers with Environment Sensitivity -
Variable Markovnikov Orientation and "cis Effect" in Ene Reactions of Nitroso...
Nitrosocarbonyl intermediates, generated at room temperature by the mild oxidation of nitrile oxides, undergo clean ene reactions with trisubstituted olefins. Allylic hydrogens...
