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dedup_wf_001--87621acd46c5aab91ef3cbb037f951a7
Background Growing evidence suggests that second-generation cryoballoon ablation (2G-CB) is effective in patients with persistent atrial fibrillation (PerAF). The cornerstone... -
How long do new medicines take to reach Canadian patients after companies fil...
Introduction Studies of the delay between when companies file a New Drug Submission (NDS) and when drugs reach Canadian patients typically focus on the time in the regulatory... -
Pharmacological characterization of potent and selective NaV1.7 inhibitors en...
Identification of voltage-gated sodium channel NaV1.7 inhibitors for chronic pain therapeutic development is an area of vigorous pursuit. In an effort to identify more potent... -
A typology of community and stakeholder engagement based on documented exampl...
Background Despite broad consensus on the importance of community and stakeholder engagement (CSE) for guiding the development, regulation, field testing, and deployment of... -
Systematic review and meta-analysis comparing Adjustable Transobturator Male ...
BACKGROUND AND PURPOSE: Urinary incontinence is one of the most serious complications of prostate cancer treatment. The objective of this study was to assess efficacy and safety... -
Ten simple rules for helping newcomers become contributors to open projects.
To survive and thrive, a community must attract new members, retain them, and help them be productive [1]. As openness becomes the norm in research, software development, and... -
Retention and promotion of women and underrepresented minority faculty in sci...
The current climate on college campuses has brought new urgency to the need to increase faculty diversity. In STEM fields particularly, the dearth of underrepresented minority... -
Haves and have nots must find a better way: The case for open scientific hard...
With the current rapid spread of COVID-19, global health systems are increasingly overburdened by the sheer number of people that need diagnosis, isolation and treatment.... -
How do research faculty in the biosciences evaluate paper authorship criteria?
Authorship on peer-reviewed journal articles and abstracts has become the main currency and reward unit in academia. Such a reward has become a crucial component for students... -
Provenance and risk in transfer of biological materials
Whereas biological materials were once transferred freely, there has been a marked shift in the formalisation of exchanges involving these materials, primarily through the use... -
False positive results of Bowie and Dick type test used for hospital steam st...
Objective To determine if the standardized B&D type test for hospital steam sterilizer is correctly indicating cycle failures in slower come-up ramps cycles. Methods... -
Harvesting prevascularized smooth muscle cell sheets from common polystyrene ...
Cell sheet engineering has recently emerged as a promising strategy for scaffold-free tissue engineering. However, the primary method of harvesting cell sheets using... -
dedup_wf_001--be43a09ea3c50d4ff744f153fc54d334
Purpose To determine whether the accuracy of two-implant model impressions taken with optical scanners was inferior to that of those taken with elastomeric materials.... -
Unilateral versus bilateral pedicle screw fixation in lumbar fusion: A system...
Objectives To carry out a systematic review on the basis of overlapping meta-analyses that compare unilateral with bilateral pedicle screw fixation (PSF) in lumbar fusion to... -
Traction force microscopy of engineered cardiac tissues
Cardiac tissue development and pathology have been shown to depend sensitively on microenvironmental mechanical factors, such as extracellular matrix stiffness, in both in vivo... -
NanoR: a user-friendly R package to analyze and compare nanopore sequencing data
AbstractMinION and GridION X5 from Oxford Nanopore Technologies are devices for real-time DNA and RNA sequencing. On the one hand, MinION is the only real-time, low cost and... -
Foldscope: Origami-Based Paper Microscope
Here we describe an ultra-low-cost origami-based approach for large-scale manufacturing of microscopes, specifically demonstrating brightfield, darkfield, and fluorescence... -
Trial registration, publication rate and characteristics in the research fiel...
OBJECTIVES: To examine 1) the publication rate of registered otology trials in ClinicalTrials.gov, 2) the public availability of the results, 3) the study characteristics... -
Use of three points to determine the accuracy of guided implantation
AIM:'This study aims to establish an open-source algorithm using Python to analyze the accuracy of guided implantation, which simplifies interstudy comparisons. METHODS:Given ≥3...
