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Enabling Policy Planning and Innovation Management through Patent Information...
Submitted by Vanessa Suane (vanessa.suane@icict.fiocruz.br) on 2016-05-05T13:03:37Z No. of bitstreams: 1 2012. Enabling policy planning and innovation management through patent... -
Risk Factors for Non-Adherence and Loss to Follow-Up in a Three-Year Clinical...
Background: Participant non-adherence and loss to follow-up can compromise the validity of clinical trial results. An assessment of these issues was made in a 3-year... -
A controlled trial of the knowledge impact of tuberculosis information leafle...
BACKGROUND: Information leaflets are widely used to increase awareness and knowledge of disease. Limited research has, to date, been undertaken to evaluate the efficacy of these... -
Animal Welfare in Studies on Murine Tuberculosis: Assessing Progress over a 1...
There is growing concern over the welfare of animals used in research, in particular when these animals develop pathology. The present study aims to identify the main sources of... -
Will Adoption of the 2010 WHO ART Guidelines for HIV-Infected TB Patients Inc...
Background: In 2010, WHO expanded previously-recommended indications for anti-retroviral treatment to include all HIV-infected TB patients irrespective of CD4 count. India,... -
What Research Is Needed to Stop TB? Introducing the TB Research Movement
With 9.4 million new cases and 1.7 million deaths worldwide in 2009, tuberculosis (TB) constitutes an unacceptable burden of human suffering and loss [1]. The tools available... -
What’s coming for health science and policy in 2018? Global experts look ahea...
In PLOS Medicine’s first editorial of 2018, editorial board members and other leading researchers share their hopes, pleas, concerns, and expectations for this year in health... -
What is the cost of diagnosis and management of drug resistant tuberculosis i...
BACKGROUND: Drug-resistant tuberculosis (DR-TB) is undermining TB control in South Africa. However, there are hardly any data about the cost of treating DR-TB in high burden... -
Tuberculosis detection and the challenges of integrated care in rural China: ...
In a Perspective accompanying Sylvia and colleagues, Carlton Evans and colleagues discuss the challenge of squaring policies around tuberculosis diagnosis with the realities of... -
Do Xpert MTB/RIF Cycle Threshold Values Provide Information about Patient Del...
INTRODUCTION: Early diagnosis and initiation to appropriate treatment is vital for tuberculosis (TB) control. The XpertMTB/RIF (Xpert) assay... -
Diagnostic accuracy of the Xpert MTB/RIF assay for bone and joint tuberculosi...
Background This study aimed to evaluate the accuracy of the Xpert MTB/RIF assay for the diagnosis of bone and joint tuberculosis. Methods We searched databases from their... -
An attempt to reproduce a previous meta-analysis and a new analysis regarding...
: Directly observed therapy (DOT) is almost universally used for the treatment of TB. Several meta-analyses using different methods have assessed the effectiveness of DOT... -
Patients Are Paying Too Much for Tuberculosis: A Direct Cost-Burden Evaluatio...
Paying for health care may exclude poor people. Burkina Faso adopted the DOTS strategy implementing "free care" for Tuberculosis (TB) diagnosis and treatment. This should... -
Predicting the impact of patient and private provider behavior on diagnostic ...
Background Tuberculosis (TB) incidence in India continues to be high due, in large part, to long delays experienced by patients before successful diagnosis and treatment... -
Development of new TB regimens : harmonizing trial design, product registrati...
International audience; • Regulatory approval of new tuberculosis (TB) drugs can be based on data from trial(s) using a surrogate endpoint of treatment efficacy under an... -
An open source pharma roadmap
In an Essay, Matthew Todd and colleagues discuss an open source approach to drug development. -
Blood Agar Validation for Susceptibility Testing of Isoniazid, Rifampicin, Et...
In recent studies, it was shown that blood agar can be used at least as effectively as Lowenstein-Jensen medium for growing Mycobacterium tuberculosis. It was also shown that... -
A novel strategy for interpreting the T-SPOT.TB test results read by an ELISP...
Background The T-SPOT.TB can be read by an ELISPOT plate imager as an alternative to a labor-intensive and time-consuming manual reading, but its accuracy has not been... -
Geographic Differences in Time to Culture Conversion in Liquid Media: Tubercu...
Background: Tuberculosis Trials Consortium Study 28, was a double blind, randomized, placebo-controlled, phase 2 clinical trial examining smear positive pulmonary Mycobacterium...
