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Secure Surveillance of Antimicrobial Resistant Organism Colonization or Infec...
Background There is stigma attached to the identification of residents carrying antimicrobial resistant organisms (ARO) in long term care homes, yet there is a need to collect... -
How well do discharge diagnoses identify hospitalised patients with community...
BACKGROUND: Credible measures of disease incidence, trends and mortality can be obtained through surveillance using manual chart review, but this is both time-consuming and... -
Developing a Buruli ulcer community of practice in Bankim, Cameroon: A model ...
Background In the Cameroon, previous efforts to identify Buruli ulcer (BU) through the mobilization of community health workers (CHWs) yielded poor results. In this paper, we... -
Rifampicin versus streptomycin for brucellosis treatment in humans: A meta-an...
Brucellosis is a zoonotic disease with a high morbidity in developing countries, but there the optimal treatment is not yet determined. Therefore, the development of a simple... -
What’s coming for health science and policy in 2018? Global experts look ahea...
In PLOS Medicine’s first editorial of 2018, editorial board members and other leading researchers share their hopes, pleas, concerns, and expectations for this year in health... -
Economic Effects of Introducing Alternative Salmonella Control Strategies in ...
The objective of the study was to analyse the economic effects of introducing alternative Salmonella control strategies in Sweden. Current control strategies in Denmark and the... -
Tuberculosis detection and the challenges of integrated care in rural China: ...
In a Perspective accompanying Sylvia and colleagues, Carlton Evans and colleagues discuss the challenge of squaring policies around tuberculosis diagnosis with the realities of... -
Do Xpert MTB/RIF Cycle Threshold Values Provide Information about Patient Del...
INTRODUCTION: Early diagnosis and initiation to appropriate treatment is vital for tuberculosis (TB) control. The XpertMTB/RIF (Xpert) assay... -
Diagnostic accuracy of the Xpert MTB/RIF assay for bone and joint tuberculosi...
Background This study aimed to evaluate the accuracy of the Xpert MTB/RIF assay for the diagnosis of bone and joint tuberculosis. Methods We searched databases from their... -
An attempt to reproduce a previous meta-analysis and a new analysis regarding...
: Directly observed therapy (DOT) is almost universally used for the treatment of TB. Several meta-analyses using different methods have assessed the effectiveness of DOT... -
Efficacy of a New Educational Tool to Improve Handrubbing Technique amongst H...
INTRODUCTION: Hand hygiene is a key component of infection control in healthcare. WHO recommends that healthcare workers perform six specific poses during each hand hygiene... -
Predicting the impact of patient and private provider behavior on diagnostic ...
Background Tuberculosis (TB) incidence in India continues to be high due, in large part, to long delays experienced by patients before successful diagnosis and treatment... -
Development of new TB regimens : harmonizing trial design, product registrati...
International audience; • Regulatory approval of new tuberculosis (TB) drugs can be based on data from trial(s) using a surrogate endpoint of treatment efficacy under an... -
An open source pharma roadmap
In an Essay, Matthew Todd and colleagues discuss an open source approach to drug development. -
A novel strategy for interpreting the T-SPOT.TB test results read by an ELISP...
Background The T-SPOT.TB can be read by an ELISPOT plate imager as an alternative to a labor-intensive and time-consuming manual reading, but its accuracy has not been... -
Do black lives matter in public health research and training?
Objective To examine whether investments made in public health research align with the health burdens experienced by white and black Americans. Methods In this... -
Will COVID-19 become the next neglected tropical disease?
The World Health Organization (WHO) currently classifies 20 diseases and conditions as neglected tropical diseases (NTDs). However, since its inception in 2007, PLOS Neglected...
