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r37980778c78--64c46fcf2abd434b500175d0e3919c54
Alzheimer’s disease (AD) is a neurodegenerative disorder that has a higher prevalence and incidence in people older than 60 years. The need for improved AD therapies is unmet as... -
GCTB sparse shrunk LD matrices from 2.8M common variants from the UK Biobank ...
GCTB sparse shrunk LD matrices from 2.8M common variants from the UK Biobank. Part AC of AA, AB, AC, AD and AE -
Demographics and clinical characteristics.
Values are mean ± standard deviation unless otherwise noted. Categorical data are compared by chi-square tests, two tailed; all other p values are by Student's t test, two tailed. -
Validity and reliability of behavioural status measures used in treatment eff...
Validity and reliability of behavioural status measures used in treatment efficacy studies in Alzheimer’s Dementia (n = 13). -
Meta-analyses of comparative efficacy of antidepressant medications on periph...
BackgroundBrain derived neurotrophic factor (BDNF) is one of the most important regulatory proteins in the pathophysiology of major depressive disorder (MDD). Increasing numbers... -
r37980778c78--45b42e6dffa4f8b7f89d4a1b011cde2b
Validity and reliability of global status measures used in treatment efficacy studies in Alzheimer’s Dementia (n = 9). -
Subjects’ characteristics.
Δ changes over 12 weeks. BMI, Body Mass Index; FM, fat mass; FFM, fat free mass; PAL, physical activity level. These data concern the as analysed population and not the as... -
Design of Peptide Substrate for Sensitively and Specifically Detecting Two Aβ...
Upregulation of neprilysin (NEP) to reduce Aβ accumulation in the brain is a promising strategy for the prevention of Alzheimer’s disease (AD). This report describes the design... -
Variability in the validity and reliability of outcome measures identified in...
IntroductionSelection of optimal outcome measures is a critical step in a systematic review; inclusion of uncommon or non-validated outcome measures can impact the uptake of... -
r37980778c78--f830f5fafab7bdb1d87d916c30c1bc00
Slow oscillations are important for consolidation of memory during sleep, and Alzheimer’s disease (AD) patients experience memory disturbances. Thus, we examined slow... -
Summary of Results.
Summary of results of follicle number counts, mRNA analyses and oxidative stress measures in ovaries of offspring born to mothers undernourished during pregnancy (UNP), during... -
GCTB sparse shrunk LD matrices from 2.8M common variants from the UK Biobank ...
GCTB sparse shrunk LD matrices from 2.8M common variants from the UK Biobank. Part AD of AA, AB, AC, AD and AE -
Participant Demographics.
1Age at enrolment,2mean value (range),3Body Mass Index,4Pre-enrolment IgA anti-tissue transglutaminase (normal range below 20 U/ml),5duration of... -
Baseline characteristics of the study population.
Values are expressed as medians (range or percentage). * Hypertension: Yes = systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg, or treated with... -
Experimental groups.
Adult male and female mice used in this study were; Mc1re, recessive yellow mice, which are null mutants with a non-functional MC1R resulting in a yellow coat colour and their... -
Cohort characteristics.
BMI, body mass index; IBD, inflammatory bowel disease; CD: Crohn's disease; UC: Ulcerative colitis. P25, P75: 25th and 75th percentiles; SD: standard deviation. *p<0.05 versus... -
Validity and reliability of cognitive measures used in treatment efficacy stu...
Validity and reliability of cognitive measures used in treatment efficacy studies of Alzheimer’s Dementia (n = 29). -
A Simple Analogue of Tumor-Promoting Aplysiatoxin Is an Antineoplastic Agent ...
Protein kinase C (PKC) is widely recognized as a therapeutic target in intractable diseases such as cancer, Alzheimer’s disease (AD), and acquired immune deficiency syndrome... -
dedup_wf_001--52d323398de494c75c4c5b7809b9bd98
Poster presented at 'Alzheimer's Association International Conference (AAIC)'; 16th-20th July 2017; London, UK. -
r37980778c78--7caf43ab2fd233a383c46cb5d2e266a4
The unfolded protein response (UPR) in the endoplasmic reticulum (ER) and the cytoplasmic heat stress response are two major stress response systems necessary for maintaining...
