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Genotype-phenotype correlations of adult-onset PLA2G6-associated Neurodegener...
Abstract Background Phospholipase A2 group VI (PLA2G6) mutations associated with neurodegeneration (PLAN) manifest as heterogeneous neurodegenerative disorders with variable... -
Retrospective analysis in oculocutaneous albinism patients for the 2.7 kb del...
Abstract Background Oculocutaneous albinism (OCA) is an autosomal recessive disorder. A significant portion of OCA patients has been found with a single pathogenic variant... -
Epidemiology of burns in pediatric patients of Beijing City
Abstract Background This study aimed to assess the epidemiological characteristics of pediatric burns in Beijing City. Methods This was a retrospective study of pediatric... -
Periostin involved in the activated hepatic stellate cells-induced progressio...
Abstract Background Incomplete thermal ablation may induce invasiveness of hepatocellular carcinoma (HCC). Here, we investigated whether activated hepatic stellate cells (HSCs)... -
Development and validation of a risk factor-based system to predict short-ter...
Abstract Background Coronavirus disease 2019 (COVID-19) has become a public health emergency of global concern. We aimed to explore the risk factors of 14-day and 28-day... -
Incidental detection of two adult gravid filarial worms in breast: a case report
Abstract Background Microfilaria is a major public health problem in tropical and subtropical countries and is an endemic problem in India. Wuchereria bancrofti is the commonest... -
Distribution of nickel and chromium containing particles from tattoo needle w...
Abstract Background Allergic reactions to tattoos are amongst the most common side effects occurring with this permanent deposition of pigments into the dermal skin layer. The... -
Epidermal grafting versus split-thickness skin grafting for wound healing (EP...
Abstract Background Split-thickness skin grafting (SSG) is an important modality for wound closure. However, the donor site becomes a second, often painful wound, which may take... -
The impairment of small nerve fibers in severe sepsis and septic shock
Abstract Background A decrease of small nerve fibers in skin biopsies during the course of critical illness has been demonstrated recently. However, the diagnostic use of skin... -
Does left ventricular hypertrophy affect cognition and brain structural integ...
Abstract Background Cognitive impairment is common in type 2 diabetes mellitus, and there is a strong association between type 2 diabetes and Alzheimer’s disease. However, we do... -
Feasibility and acceptance of exercise recommendations (10,000 steps a day) w...
Abstract Background Benefits of exercise to prevent non-communicable diseases are well-documented. Limited data exists to promote physical activity in healthy but sedentary... -
Association between antimicrobial usage, biosecurity measures as well as farm...
Abstract Background Antimicrobial usage in food producing animals is of major concern. A clear link between the extent of use and the development of antimicrobial resistance has... -
Ethnopharmacological survey of medicinal plants used by patients with psorias...
Abstract Background Psoriasis is a frequent skin inflammatory disorder that inflicts millions of patients around the globe. To meet their healthcare needs, patients with... -
A double-blind, randomised, placebo-controlled study of roxithromycin and dox...
Abstract Background Azithromycin prophylaxis has been shown to reduce COPD exacerbations but there is poor evidence for other antibiotics. We compared exacerbation rates in COPD... -
TSS seq based core promoter architecture in blood feeding Tsetse fly (Glossin...
Abstract Background Transcription initiation regulation is mediated by sequence-specific interactions between DNA-binding proteins (transcription factors) and cis-elements,... -
Genetic and clinical characterization of 73 Pigmentary Mosaicism patients: re...
Abstract Background Pigmentary mosaicism constitutes a heterogeneous group of skin pigmentation alterations associated with multisystem involvement. The aim of this study was to... -
A multimodal intervention to improve hand hygiene compliance in peripheral wa...
Abstract Background Interventions to improve hand hygiene (HH) compliance are a key element in the practice infection prevention and control. It was our objective to assess the... -
Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrat...
Abstract Background Zyflamend, a blend of herbal extracts, effectively inhibits tumor growth using preclinical models of castrate-resistant prostate cancer mediated in part by... -
Protocol for the systematic review of the prevention, treatment and public he...
Abstract Background Impetigo, scabies, and fungal skin infections disproportionately affect populations in resource-limited settings. Evidence for standard treatment of skin... -
First-dollar cost-sharing for skilled nursing facility care in medicare advan...
Abstract Background The initial days of a Medicare-covered skilled nursing facility (SNF) stay may have no cost-sharing or daily copayments depending on beneficiaries’...
