30 items found

Tags: 60506 Virology Biophysics mesheuropmc.viruses

Filter Results
  • dataset

    r37980778c78--8399dcd6126cbccf560ecdaa787c2261

    Mouse APOBEC3 (mA3) inhibits murine leukemia virus (MuLV) replication by a deamination-independent mechanism in which the reverse transcription is considered the main target...
  • dataset

    r37980778c78--f318cc161eba445b3e4a63f4de9134ad

    Influenza polymerase is a heterotrimer composed of polymerase acidic protein A (PA) and basic proteins 1 (PB1) and 2 (PB2). The endonuclease active site, located in the PA...
  • dataset

    dedup_wf_001--777cfbb2441186cdb483ef84cad657b0

    Additional file 1. Origin and Accession # of recently emerged SARS coronaviruses and viral RdRps.
  • dataset

    r37980778c78--30cb3f18a7ac88318aec33256f5ef27b

    Trigocherrin A, a chlorinated and highly oxygenated daphnane diterpenoid orthoester (DDO), was isolated from the bark of Trigonostemon cherrieri. Trigocherrin A is the first...
  • dataset

    fitness

    Fitness estimates for each strain relative to the isogenic phage free strain. The proportion of lysogens identified among the originally phage free competitor strain is also...
  • dataset

    miR-124 attenuates Japanese encephalitis virus replication by targeting DNM2

    Abstract Background Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes acute viral encephalitis in humans. Pigs are important amplifier hosts of JEV....
  • dataset

    Structural alteration of DNA induced by viral protein R of HIV-1 triggers the...

    Abstract Background Viral protein R (Vpr) is an accessory protein of HIV-1, which is potentially involved in the infection of macrophages and the induction of the...
  • dataset

    r37980778c78--f3cede1fc398b346277647f5f1d9ac73

    Socio-demographic characteristics of the population studied according to the presence of Zika, dengue or chikungunya diagnosis.
  • dataset

    Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer

    Structural rearrangements of HIV-1 glycoprotein Env promote viral entry through membrane fusion. Env is a symmetric homotrimer with each protomer composed of surface subunit...
  • dataset

    RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupan...

    In mammalian cells, widespread acceleration of cytoplasmic mRNA degradation is linked to impaired RNA polymerase II (Pol II) transcription. This mRNA decay-induced...
  • dataset

    Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in h...

    Productive infection of human parvovirus B19 (B19V) exhibits high tropism for burst forming unit erythroid (BFU-E) and colony forming unit erythroid (CFU-E) progenitor cells in...
  • dataset

    Additional file 3: of Multiple molecular detection of respiratory viruses and...

    Agreement between paired nasopharyngeal swabs and tracheal washes for the detection of viral genome by qPCR. EHV: equid herpesvirus; ERBV: equine rhinitis virus B; EAdV-1:...
  • dataset

    Biochemical characterization of recombinant influenza A polymerase heterotrim...

    Influenza polymerase is a heterotrimer protein with both endonuclease and RNA-dependent RNA polymerase (RdRp) activity. It plays a critical role in viral RNA replication and...
  • publication

    dedup_wf_001--7a9f1a8a155672cd9f9f554901862a55

    Appendix Formal definition of structural virality and normalized structural virality. (DOCX 25 kb)
  • publication

    Additional file 3: of Multiple molecular detection of respiratory viruses and...

    Agreement between paired nasopharyngeal swabs and tracheal washes for the detection of viral genome by qPCR. EHV: equid herpesvirus; ERBV: equine rhinitis virus B; EAdV-1:...
  • publication

    dedup_wf_001--7fe63a7eb59defaff34492ecfbc087f5

    Summary illustration. Model for HDAC6-mediated A3G protection and control of HIV-1 infectiveness. HDAC6 directly interacts and forms a constitutive complex with A3G. This...
  • other

    Structural alteration of DNA induced by viral protein R of HIV-1 triggers the...

    Abstract Background Viral protein R (Vpr) is an accessory protein of HIV-1, which is potentially involved in the infection of macrophages and the induction of the...
  • other

    miR-124 attenuates Japanese encephalitis virus replication by targeting DNM2

    Abstract Background Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes acute viral encephalitis in humans. Pigs are important amplifier hosts of JEV....
  • other

    The matrix domain contributes to the nucleic acid chaperone activity of HIV-2...

    Abstract Background The Gag polyprotein is a multifunctional regulator of retroviral replication and major structural component of immature virions. The nucleic acid chaperone...
  • other

    Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeuti...

    Abstract Background The Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) outbreak originating in Wuhan, China, has raised global health concerns and the...