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Managing sequence-dependent setup times - The target conflict between output ...
Sequence-dependent setup times cause a trade-off between output rate, WIP and fluctuating throughput times. Companies usually face this trade-off by bundling similar orders in... -
The impairment of small nerve fibers in severe sepsis and septic shock
Abstract Background A decrease of small nerve fibers in skin biopsies during the course of critical illness has been demonstrated recently. However, the diagnostic use of skin... -
Suspicion of respiratory tract infection with multidrug-resistant Enterobacte...
Abstract Background Multidrug-resistant (MDR) infections are a serious concern for children admitted to the Paediatric Intensive Care Unit (PICU). Tracheal colonization with MDR... -
Increasing the treatment motivation of patients with somatic symptom disorder...
Abstract Background Therapeutic intervention programs for somatic symptom disorder (SSD) show only small-to-moderate effect sizes. These effects are partly explained by the... -
Infection prevention and control measures and tools for the prevention of ent...
Abstract Background Infections with carbapenem-resistant Enterobacteriaceae (CRE) are increasingly being reported from patients in healthcare settings. They are associated with... -
Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) and proteinuria pre...
Abstract Background Nephropathia epidemica (NE) is a mild form of hemorrhagic fever with renal syndrome (HFRS) that is caused by the Puumala virus. Periodic outbreaks have been... -
Safety and efficacy of the choline analogue SAR97276 for malaria treatment: r...
Abstract Background Malaria remains one of the most important infectious diseases. Treatment options for severe malaria are limited and the choline analogue SAR97276A is a novel... -
A randomised, double-blind clinical phase II trial of the efficacy, safety, t...
Abstract Background The clinical development of a single encounter treatment for uncomplicated malaria has the potential to significantly improve the effectiveness of...
