-
Adolescent BMI and early-onset type 2 diabetes among Ethiopian immigrants and...
Abstract Background We assessed in a nationwide cohort the association between adolescent BMI and early-onset ( -
Investigation of sex-specific effects of apolipoprotein E on severity of EAE ...
Abstract Background Despite pleiotropic immunomodulatory effects of apolipoprotein E (apoE) in vitro, its effects on the clinical course of experimental autoimmune... -
Bioavailability of subcutaneous and intramuscular administrated buprenorphine...
Abstract Background Buprenorphine is one of the most used analgesics for postoperative pain in rabbits. The recommended dose in rabbits (0.01–0.05 mg/kg) is the same for... -
Correction to: SALP, a new single-stranded DNA library preparation method esp...
After publication of the original article [1] the authors noted that the additional files had not been uploaded correctly. -
Dried blood spot versus venous blood sampling for phenylalanine and tyrosine
Abstract Background This study investigated the agreement between various dried blood spot (DBS) and venous blood sample measurements of phenylalanine and tyrosine... -
Exposure to perfluorooctanoic acid (PFOA) decreases neutrophil migration resp...
Abstract Objective Perfluorooctanoic acid (PFOA) is a ubiquitous environmental contaminant and a known immune suppressant in humans and experimental animal models. Studies on... -
The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzhe...
Abstract Background Synaptic degeneration is a central pathogenic event in Alzheimer’s disease that occurs early during the course of disease and correlates with cognitive... -
Genome-wide DNA methylation at birth in relation to in utero arsenic exposure...
Abstract Background In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life.... -
Purification and characterization of a novel glutamate dehydrogenase from Geo...
Abstract Crude enzyme from Geotrichum candidum S12 exhibited high activity towards hexanol at pH 4.0, distinguishing it from currently known enzymes. To identify the dominant... -
CRISPR/dCas9-mediated transcriptional improvement of the biosynthetic gene cl...
Abstract Background The CRISPR/dCas9 system is a powerful tool to activate the transcription of target genes in eukaryotic or prokaryotic cells, but lacks assays in complex... -
Increased calcium intake is associated lower serum 25-hydroxyvitamin D levels...
Abstract Background There are indications that an increased intake of calcium has a vitamin D sparing effect, which might be explained by a decreased catabolism of... -
Next-generation sequencing analysis of receptor-type tyrosine kinase genes in...
Abstract Background Improvement in genetic characterization of Colon Cancer (CC) patients is required to propose new potential targets, since surgical resection coupled to... -
Sex hormones affect endothelial lipase-mediated lipid metabolism and atherosc...
Abstract Background Endothelial lipase (EL) plays an important role in lipoprotein metabolism and atherosclerosis. To study the functional roles of EL, we recently generated... -
Cherenkov luminescence imaging is a fast and relevant preclinical tool to ass...
Abstract Purpose Molecular imaging techniques visualise biomarkers for both drug development and personalised medicine. In this field, Cherenkov luminescence imaging (CLI) seems... -
Simplified Chinese version of hip and knee replacement expectations surveys i...
Abstract Background The Hospital for Special Surgery Hip Replacement Expectations Survey (HSS-THRES) and Knee Replacement Expectations Survey (HSS-TKRES) are widely used tools... -
Molecular characterization of flavanone 3-hydroxylase gene and flavonoid accu...
Abstract Background Among secondary metabolites, flavonoids are particularly crucial for plant growth, development, and reproduction, as well as beneficial for maintenance of... -
Biomarkers of food intake for Allium vegetables
Abstract Allium vegetables are widely consumed around the world and are known for their potential bioactive components improving human health. These effects have been... -
Development of gut inflammation in mice colonized with mucosa-associated bact...
Abstract Background Disturbances in the intestinal microbial community (i.e. dysbiosis) or presence of the microbes with deleterious effects on colonic mucosa has been linked to... -
Comparison of biochemical parameters among DPP4 inhibitor users and other ora...
Abstract Background Higher efficacy of incretin-based therapies for type 2 diabetes mellitus has been reported from Asia. Pancreatitis and hepatitis have also been suspected to... -
Expression of adiponectin in the subchondral bone of lumbar facet joints with...
Abstract Background Osteoarthritis research has been most commonly performed in the setting of the articular cartilage of the knee. To the best of our knowledge, no studies have...
