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Knowledge of obstetric danger signs and associated factors among pregnant wom...
Abstract Background Knowledge of danger signs of obstetric complications is first step in the appropriate and timely referral to essential obstetric care. Although women’s... -
Helios + Regulatory T cell frequencies are correlated with control of viral r...
Abstract Background The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation.... -
UK national clinical audit: management of pregnancies in women with HIV
Abstract Background The potential for HIV transmission between a pregnant woman and her unborn child was first recognized in 1982. Since then a complex package of measures to... -
Climate factors driven typhus group rickettsiosis incidence dynamics in Xishu...
Abstract Background Typhus group rickettsiosis (TGR), which is a neglected vector-borne infectious disease, including epidemic typhus and endemic typhus. We explored the lag... -
Using predicate and provenance information from a knowledge graph for drug ef...
Abstract Background Biomedical knowledge graphs have become important tools to computationally analyse the comprehensive body of biomedical knowledge. They represent knowledge... -
The potential role of infectious agents and pelvic inflammatory disease in ov...
Abstract Background The etiological cause of ovarian cancer is poorly understood. It has been theorized that bacterial or viral infection as well as pelvic inflammatory disease... -
Estimating the cost-effectiveness of daclatasvir + sofosbuvir versus sofosbuv...
Abstract Background As treatments for chronic hepatitis C are moving away from interferon-containing regimens, the most appropriate allocation of resources to higher cost,... -
To evaluate the efficacy and safety of PLC in perimenopausal or postmenopausa...
Abstract Background Hot flashes are the most frequent symptoms of the menopause, with 10–20% of all postmenopausal women reporting nearly intolerable occurrences. Although... -
Burden of chronic kidney disease on the African continent: a systematic revie...
Abstract Background Accurate contemporary data on the burden of Chronic Kidney Disease (CKD) on the African continent are lacking. We determined the prevalence of CKD in adult... -
Community-onset sepsis and its public health burden: a systematic review
Abstract Background Sepsis is a life-threatening condition and major contributor to public health and economic burden in the industrialised world. The difficulties in accurate... -
Gene expression prediction using low-rank matrix completion
Abstract Background An exponential growth of high-throughput biological information and data has occurred in the past decade, supported by technologies, such as microarrays and... -
Real-time crustal monitoring system of Japanese Islands based on spatio-tempo...
Abstract To continuously monitor crustal behavior associated with earthquakes, magmatic activities and other environmental effects (e.g., tides and rain precipitation), we have... -
Estimating the impact post randomization changes in staff behavior in infecti...
Abstract Background Randomized controlled trials (RCTs) of behavior-based interventions are particularly vulnerable to post-randomization changes between study arms. We assess... -
Clinical vignettes and global health considerations of infertility care in un...
Abstract The ability to receive standard of care for a diagnosis of infertility is a factor of oneâ s financial state and educational level, which are often correlated.... -
Assessment of research waste part 1: an exemplar from examining study design,...
Abstract Background Research waste is estimated to be very common, but assessments of its prevalence and scope are rare. As an example, we assessed research waste in clinical... -
Healthcare utilization and direct costs of non-infectious comorbidities in HI...
Objective: To estimate the incremental healthcare utilization and costs associated with common non-infectious comorbid conditions among commercially and Medicaid-insured... -
The use of empirical research in bioethics: a survey of researchers in twelve...
Abstract Background The use of empirical research methods in bioethics has been increasing in the last decades. It has resulted in discussions about the ‘empirical turn of... -
How effective are digital interventions in increasing flu vaccination amongst...
Abstract Background Pregnant women and their unborn babies are at increased risk of complications as a result of flu, yet uptake of the flu vaccination in the UK remains low.... -
Systematic literature review and meta-analysis of the efficacy of artemisinin...
Abstract Background There is no agreed standard method to assess the efficacy of anti-malarials for uncomplicated falciparum in pregnancy despite an increased risk of adverse... -
Sublingual microcirculation does not reflect red blood cell transfusion thres...
Abstract Purpose Hemoglobin (Hb) transfusion thresholds are established in intensive care units. A restrictive transfusion threshold (Hb 70–75 g/l) is recommended in septic...
