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Engineering the enolase magnesium II binding site: implications for its evolu...
The glycolytic enzyme enolase catalyzes the reversible elimination of water from 2-phosphoglycerate (2-PGA) to form phosphoenolpyruvate (PEP). Two magnesium ions in the active... -
Structure-Guided Design of <i>C</i><sub>2</sub>-Symmetric HIV-1 Protease Inhi...
Infections with the human immunodeficiency virus, which inevitably lead to the development of AIDS, are still among the most serious global health problems causing more than 2.5...