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Revisiting the Ullmann−Ether Reaction: A Concise and Amenable Synthesis of N...
A concise synthesis of a series of novel dibenzoxepino[4,5-d]pyrazoles was accomplished by implementation of an intramolecular Ullmann-ether reaction on... -
r37980778c78--f427978cee3bbb3c3e1923ab639a3fd7
The introduction of sterically isolating ortho-trialkylsilyl, -aryldialkylsilyl, and -diarylalkylsilyl substituents onto the structurally preorganized... -
r37980778c78--b2b79e004106aa9ee47073d0a69eeb71
Alkylidene indane and ring-expanded scaffolds have been prepared using an enantioselective crotylation/Heck cyclization sequence. Further diversification using consecutive... -
r37980778c78--36d0633ab26a227dc67f01752712b032
Calmodulin (CaM) regulates calcium release from intracellular stores in skeletal muscle through its association with the ryanodine receptor (RyR1) calcium release channel, where... -
r37980778c78--7e22463b7cf86612fa966babbc025add
An unprecedented enantioselective deprotonation/conjugate elimination sequence, which transforms an allylic meso-dioxepane into a chiral diene, is described. The best...
