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Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,...
Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to eliminate potential in vivo hydrolysis to a... -
r37980778c78--56fcee8741a21a8729fa2db393bd30b0
Design, synthesis, and in vitro bioevaluation of a new class of potential dual PPARα and γ agonists discovered through a structure-driven design paradigm are described. The... -
A Logic Modelling Workflow For Systems Pharmacology
Modern biology has made great advances in our knowledge of the workings of organisms at the molecular level. Although there is still much to be learned in this area, many... -
System boundary selection in life-cycle inventories using hybrid approaches
Life-cycle assessment (LCA) is a method for evaluating the environmental impacts of products holistically, including direct and supply chain impacts. The current LCA... -
Access Control
Publisher Summary Access control is the control of access to property, services, events, or information, and is a combination of several things including control, record... -
Design of Novel Derivatives of Phosphonoformate (Foscarnet) as Prodrugs and A...
Design of Novel Derivatives of Phosphonoformate (Foscarnet) as Prodrugs and Antiviral Agents -
r37980778c78--fe4e83e064bdf00dc834ea490c40288c
A ratiometric fluorescent biosensor for Hg2+ is constructed from the MerR protein and a duplex DNA containing a pyrene excimer. -
Discovery of Potent 3,5-Diphenyl-1,2,4-oxadiazole Sphingosine-1-phosphate-1 (...
A class of 3,5-diphenyl-1,2,4-oxadiazole based compounds have been identified as potent sphingosine-1-phosphate-1 (S1P1) receptor agonists with minimal affinity for the S1P2 and... -
Inherently Chiral Biscalix[4]arenes: Design and Syntheses
Inherently chiral biscalix[4]arenes have been designed and synthesized by covalently assembling two calix[4]arene building blocks in a 1,3-position linking with 1,2-position... -
r37980778c78--566516baee56754d67c275c2225a172b
We previously prepared the oligonucleotides (ODNs) conjugated to an anthraquinone (AQ) group via one carbon linker at the 2′-sugar position. When these modified ODNs bind to... -
Lexical Means And Illocutionary Acts In Western Zhou Political Ideology
Event Date: May 2, 2012 Organization: Israel Institute of Advanced Studies -
Ventajas del formato ePub para la difusión de contenidos en Humanidades: just...
Una versión en pdf del contenido está disponible en https://doi.org/10.5281/zenodo.2580057 -
A Ti<sub>2</sub>Ru<sub>2</sub>Pd<sub>2</sub> Oxo−Sulfido Cluster Synthesized ...
A Ti2Ru2Pd2 Oxo−Sulfido Cluster Synthesized by Linking Two Rationally Preorganized TiRuPdS2 Heterotrimetallic Units with an Oxo Ligand: Its Reaction with an Alkyne -
dedup_wf_001--6210dd069d84280759634e1b84310032
The current research project seeks for design exploration strategies that can accommodate the flexible and ambiguous nature of creative exploration in early design phases, while... -
dedup_wf_001--7387488b176d100ed9aa0bcd3418a5ee
Presentation at the RDA & the humanities. Network meeting in Denmark. Information about the event -
r37980778c78--8ed458fc46b46e50526a39ec3d4c93da
A new modification of 2−5A-antisense, 2−5A-iso-antisense, has been developed based on a reversal of the direction of the polarity of the antisense domain of a 2−5A-antisense... -
Additional file 9: of f-treeGC: a questionnaire-based family tree-creation so...
Model pedigrees of scenarios outlined (a) Scenario D, (b) scenario P. (PPTX 389 kb) -
Damage potential of Drosophila suzukii and development of phytosanitary measu...
Slide of the Euphresco project 'Damage potential of Drosophila suzukii and development of phytosanitary measures' (DROSKII) Project funded through the Euphresco network -
Additional file 6: Figure S5. of Follistatin is a metastasis suppressor in a ...
FST expression is associated with overall survival and metastasis in multiple cohorts of patients with breast cancer. Tumors are stratified into the highest 10% and lowest... -
Design of Organocatalysts for Asymmetric Direct Syn-Aldol Reactions
Two new organocatalysts 3a and 3b, derived from l-leucine and (S)-β-amino alcohols that were prepared from l-valine, were designed and afforded the direct syn-aldol reactions of...
