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Identifying clinical subgroups in IgG4-related disease patients using cluster...
Abstract Background To explore the clinical patterns of patients with IgG4-related disease (IgG4-RD) based on laboratory tests and the number of organs involved. Methods... -
New-onset non-infectious pulmonary manifestations among patients with systemi...
Abstract Objective The objective was to estimate the incidence of lung disease among patients with systemic lupus erythematosus (SLE). Methods Using Swedish register data, we... -
Long-term follow-up after scleral lens fixation in patients with Marfan syndrome
Abstract Background The dislocation of the crystalline lens is a common finding in patients with Marfan syndrome (MFS). Scleral intraocular lens (IOL) fixation is an accepted... -
Perceived causes and risk factors of Buruli ulcer among patients at Agogo Pre...
Abstract Objective The incidence of Buruli ulcer has been recorded in about 30 countries globally and Africa seems to be the most affected area. The study sought to determine... -
Establishing the acceptability of a brief patient reported outcome measure an...
Abstract Background To examine the acceptability of a Patient Reported Outcome Measure (PROM) that assesses perceptions and experiences of implants for breast reconstruction or... -
Optimizing adalimumab treatment in psoriasis with concomitant methotrexate (O...
Abstract Background The introduction of anti-tumor necrosis factor medications has revolutionized the treatment of psoriasis with achievement of treatment goals (Psoriasis Area... -
Health-related quality of life in systemic sclerosis compared with other rheu...
Abstract Background Systemic sclerosis (SSc) is a rare autoimmune disease characterized by fibrosis of the skin and the involvement of multiple internal organs. Previous studies... -
Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17...
Abstract Background Circ-ITCH is a circRNA generated from several exons of itchy E3 ubiquitin protein ligase (ITCH) and tumor suppressor served as a sponge for certain miRNAs... -
Global, regional, and national burdens of bladder cancer in 2017: estimates f...
Abstract Background The aim of this study is to describe the prevalence and mortality of bladder cancer (BCa) using data obtained in the Global Burden of Disease study performed... -
Adjuvant trastuzumab duration trials in HER2 positive breast cancer – what re...
Abstract Background Twelve months treatment is the current standard of care for adjuvant trastuzumab in patients with HER2 positive early breast cancer however the optimal... -
Estimating the impact post randomization changes in staff behavior in infecti...
Abstract Background Randomized controlled trials (RCTs) of behavior-based interventions are particularly vulnerable to post-randomization changes between study arms. We assess... -
Low expression of estrogen receptor β in T lymphocytes and high serum levels ...
Abstract Background Current evidence indicates that estrogens, in particular 17β-estradiol (E2), play a crucial role in the gender bias of autoimmune diseases although the... -
NatHER: protocol for systematic evaluation of trends in survival among patien...
Abstract Background Human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) is an aggressive form of breast cancer and is historically associated... -
Levels of CXCL13 and sICAM-1 correlate with disease activity score in patient...
Abstract Background Tocilizumab (TCZ), a humanized monoclonal antibody against the interleukin-6 receptor, has been proven to be a safe and effective treatment for rheumatoid... -
Will savings from biosimilars offset increased costs related to dose escalati...
Abstract Introduction Biosimilar infliximab has the potential for appreciable cost savings compared to its reference biologic, but dose escalation is common and increases costs.... -
HERMIONE: a randomized Phase 2 trial of MM-302 plus trastuzumab versus chemot...
Abstract Background Human epidermal growth factor receptor 2 (HER2)-positive breast cancer is a particularly aggressive form of the disease, and ultimately progresses in... -
NT-proBNP correlates with LVEF decline in HER2-positive breast cancer patient...
Abstract Background Early identification of cardiac dysfunction by non-invasive imaging in HER2-positive breast cancer patients treated with trastuzumab is challenging. In... -
High-frequency ultrasound of the skin in systemic sclerosis: an exploratory s...
Abstract Background Thickened skin is a major clinical feature in patients with systemic sclerosis (SSc). We investigated changes of skin thickness in patients with SSc using... -
Comparison among ACR1997, SLICC and the new EULAR/ACR classification criteria...
Abstract Background To date there are no specific classification criteria for childhood-onset systemic lupus erythematosus (cSLE). This study aims to compare the performance... -
Cost effectiveness and affordability of trastuzumab in sub-Saharan Africa for...
Abstract Background Breast cancer is the second most common cancer worldwide, the most common among women, and the most frequent cause of death among women in less developed...
