-
Regulation of STEP61 and tyrosine-phosphorylation of NMDA and AMPA receptors ...
Abstract Background Sustained changes in network activity cause homeostatic synaptic plasticity in part by altering the postsynaptic accumulation of N-methyl-D-aspartate... -
Characterization of a thalamic nucleus mediating habenula responses to change...
Abstract Background Neural activity in the vertebrate habenula is affected by ambient illumination. The nucleus that links photoreceptor activity with the habenula is not well... -
Ca2+ in the dorsal raphe nucleus promotes wakefulness via endogenous sleep-wa...
Abstract Serotonergic neurons in the dorsal raphe nucleus (DRN) are involved in the control of sleep-wake states. Our previous studies have indicated that calcium (Ca2+)... -
The affordability of a healthy and sustainable diet: an Australian case study
Abstract Background/Aims EAT–Lancet Commission’s Planetary Health Diet proposed a diet that integrates nutrition and sustainability considerations, however its affordability is... -
The potassium channel KCa3.1 represents a valid pharmacological target for mi...
Abstract Background Recent studies described a critical role for microglia in Parkinson’s disease (PD), where these central nerve system resident immune cells participate in the... -
Bioinformatics analysis of glial inflammatory responses to air pollution
Bioinformatics analysis of glial inflammatory responses to air pollution -
Knowledge and attitudes about transcranial magnetic stimulation among psychia...
Abstract Background Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive form of brain stimulation. It has been used in many mental health institutions to treat... -
Memory retrieval in addiction: a role for miR-105-mediated regulation of D1 r...
Abstract Background Drug addiction is a chronic brain disorder characterized by the compulsive use of drugs. The study of chronic morphine-induced adaptation in the brain and... -
A video protocol for rapid dissection of mouse dorsal root ganglia from defin...
Abstract Objective Dorsal root ganglia (DRG) are heterogeneous assemblies of assorted sensory neuron cell bodies found in bilateral pairs at every level of the spinal column.... -
How to improve patient education on deep brain stimulation in Parkinson’s dis...
Abstract Background The introduction of deep brain stimulation (DBS) about 25 years ago provided one of the major breakthroughs in the treatment of Parkinson’s disease (PD).... -
The Bdnf and Npas4 genes are targets of HDAC3-mediated transcriptional repres...
Abstract Background Histone deacetylase-3 (HDAC3) promotes neurodegeneration in various cell culture and in vivo models of neurodegeneration but the mechanism by which HDAC3... -
Minimally invasive microendoscopy system for in vivo functional imaging of de...
The ability to image neurons anywhere in the mammalian brain is a major goal of optical microscopy. Here we describe a minimally invasive microendoscopy system for studying the... -
Deficits in coordinated neuronal activity and network topology are striatal h...
Abstract Background Network alterations underlying neurodegenerative diseases often precede symptoms and functional deficits. Thus, their early identification is central for... -
Unilateral intranigral administration of β-sitosterol β-D-glucoside triggers ...
Abstract The spreading and accumulation of α-synuclein and dopaminergic neurodegeneration, two hallmarks of Parkinson’s disease (PD), have been faithfully reproduced in rodent... -
Impact of blunt chest trauma on outcome after traumatic brain injury– a match...
Abstract Background Traumatic brain injury (TBI) is associated with high rates of long-term disability and mortality. Our aim was to investigate the effects of thoracic trauma... -
Time dependent degeneration of the nigrostriatal tract in mice with 6-OHDA le...
Abstract Background Accurately assessing promising therapeutic interventions for human diseases depends, in part, on the reproducibility of preclinical disease models. With the... -
Yy1 regulates Senp1 contributing to AMPA receptor GluR1 expression following ...
Abstract Background Neuronal activity-induced changes in gene expression patterns are important mediators of neuronal plasticity. Many neuronal genes can be activated or... -
Loop diuretic use in patients with AKI: different severity, different response
Loop diuretic use in patients with AKI: different severity, different response -
A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumu...
Abstract Background Multiple system atrophy (MSA) is a progressive, neurodegenerative disease characterized by parkinsonism, resistance to dopamine therapy, ataxia, autonomic... -
ADHD-related sex differences in fronto-subcortical intrinsic functional conne...
Abstract Background Attention-deficit/hyperactivity disorder (ADHD) is associated with atypical fronto-subcortical neural circuitry and heightened delay discounting, or a...