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    Brain activation to high-calorie food images in healthy normal weight and obe...

    Abstract Background Understanding how normal weight and obese young children process high-calorie food stimuli may provide information relevant to the neurobiology of eating...
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    Analysis of survival after initiation of continuous renal replacement therapy...

    Abstract Background No study has specifically investigated the duration of continuous renal replacement therapy (CRRT) in patients who experienced acute kidney injury during...
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    MRI of trunk muscles and motor and respiratory function in patients with myot...

    Abstract Background Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to...
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    Rubidium and potassium levels are altered in Alzheimer’s disease brain and bl...

    Abstract Loss of intracellular compartmentalization of potassium is a biochemical feature of Alzheimer’s disease indicating a loss of membrane integrity and mitochondrial...
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    18F-VC701-PET and MRI in the in vivo neuroinflammation assessment of a mouse ...

    Abstract Background Positron emission tomography (PET) using translocator protein (TSPO) ligands has been used to detect neuroinflammatory processes in neurological disorders,...
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    Oxidative stress and premature senescence in corneal endothelium following pe...

    Abstract Background The purpose of this study was to address the question of how the premature senescence process may affect corneal endothelium after penetrating keratoplasty,...
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    Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammatio...

    Abstract Background The interaction between astrocytes and microglia plays a vital role in the damage and repair of brain lesions due to traumatic brain injury (TBI). Recent...
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    ICEAGE (Incidence of Complications following Emergency Abdominal surgery: Get...

    Abstract Background Postoperative complications and delayed physical recovery are significant problems following emergency abdominal surgery. Physiotherapy aims to aid recovery...
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    Dried blood spot versus venous blood sampling for phenylalanine and tyrosine

    Abstract Background This study investigated the agreement between various dried blood spot (DBS) and venous blood sample measurements of phenylalanine and tyrosine...
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    Erythropoietin as an add-on treatment for cognitive side effects of electroco...

    Abstract Background Electroconvulsive therapy (ECT) is the most effective treatment for severe depression, but its use is impeded by its cognitive side effects. Novel treatments...
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    Involvement of ABC-transporters and acyltransferase 1 in intracellular choles...

    Abstract Background Understanding pathogenic mechanisms is imperative for developing novel treatment to the tuberculosis, an important public health burden worldwide. Recent...
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    Potential gains in life expectancy by reducing inequality of lifespans in Den...

    Abstract Background Reducing lifespan inequality is increasingly recognized as a health policy objective. Whereas lifespan inequality declined with rising longevity in most...
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    Cardiovascular health effects following exposure of human volunteers during f...

    Abstract Background Firefighters have increased risk of cardiovascular disease and of sudden death from coronary heart disease on duty while suppressing fires. This study...
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    Pleural effusion from intrathoracic migration of a ventriculo-peritoneal shun...

    Abstract Background Pleural effusion is a rare complication of ventriculo-peritoneal (VP) cerebrospinal fluid (CSF) shunting and its diagnosis is difficult in patients with...
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    Effects of very early start of norepinephrine in patients with septic shock: ...

    Abstract Background Optimal timing for the start of vasopressors (VP) in septic shock has not been widely studied since it is assumed that fluids must be administered in...
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    Autonomic nervous system response to remote ischemic conditioning: heart rate...

    Abstract Background Remote ischemic conditioning (RIC) is a procedure applied in a limb for triggering endogenous protective pathways in distant organs, namely brain or heart....
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    Excessive carbohydrate consumption and body mass index: the risk factors for ...

    Abstract Background Prader-Willi syndrome (PWS) is commonly associated with severe obesity and type 2 diabetes mellitus (T2DM) and is caused by excessive eating. Only very few...
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    How to deal with a temporary suspension and restarting your trial: our experi...

    Abstract Whilst the issues around early termination of randomised controlled trials (RCTs) are well documented in the literature, trials can also be temporarily suspended with...
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    Serum progesterone distribution in normal pregnancies compared to pregnancies...

    Abstract Background Progesterone is a critical hormone in early pregnancy. A low level of serum progesterone is associated with threatened miscarriage. We aim to establish the...
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    An enhanced recovery after surgery program in orthopedic surgery: a systemati...

    Abstract Objectives There is an increased interest in enhanced recovery after surgery (ERAS) minimizing adverse events after orthopedic surgery. Little consensus supports the...