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An ecological analysis of food outlet density and prevalence of type II diabe...
Abstract Background Studies suggest that the built environment with high numbers of fast food restaurants and convenience stores and low numbers of super stores and grocery... -
Perioperative surgery- and anaesthesia-related risks of laparoscopic Roux-en-...
Abstract Background Conservative obesity treatment often leads to limited results. Bariatric surgery is highly efficient, but the candidates are at risk of developing... -
The effect of cigarette smoking on the oral and nasal microbiota
Abstract Background The goal of the study was to investigate whether cigarette smoking alters oral and nasal microbial diversity, composition, and structure. Twenty-three... -
Transcriptionally promiscuous "blurry" promoters in Tc1/mariner transposons a...
Abstract Background We have recently described a peculiar feature of the promoters in two Drosophila Tc1-like elements, Bari1 and Bari3. The AT-richness and the presence of weak... -
Association between E469K polymorphism in the ICAM1 gene and the risk of diab...
Abstract Background Inflammation may be a key pathophysiological mechanism in diabetic nephropathy (DN). Intercellular adhesion molecule 1 (ICAM1) is an acute phase marker of... -
Temporal trends of dialysis requiring acute kidney injury after orthotopic ca...
Abstract Background The epidemiology and outcomes of acute kidney injury (AKI) in prevalent non-renal solid organ transplant recipients is unknown. Methods We assessed the... -
iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated d...
Abstract Background Previous research indicated that nitric oxide synthase (NOS) is the key molecule for S-nitrosylation of ryanodine receptor 1 (RyR1) in DMD model mice (mdx... -
Health related quality of life in chronic kidney disease; a descriptive study...
Abstract Introduction The current epidemic of chronic kidney disease (CKD) in Sri Lanka is ascribed to the exponential increase in the number of CKD patients, which cannot be... -
High frequency optogenetic activation of inputs to the lateral amygdala forms...
Abstract Aim A hallmark of classical conditioning is that conditioned stimulus (CS) must be tightly coupled with unconditioned stimulus (US), often requiring temporal overlap... -
Modified bolster dressing with continuous suction improves skin graft surviva...
Abstract Background Skin engraftment of intraoral defects is known to be inconsistent due to mobility of the oral structure, uneven wounds, and accumulation of saliva under the... -
Pilot non dialysis chronic renal insufficiency study (P-ND-CRIS): a pilot stu...
Abstract Background Before establishing a prospective cohort, an initial pilot study is recommended. However, there are no precise guidelines on this subject. This paper reports... -
Long-term survival and prognostic factors for locally advanced renal cell car...
Abstract Background Previous related studies have mainly focused on renal cell carcinoma (RCC) with venous tumor thrombus, specifically inferior vena cava tumor thrombus with... -
Selection of reliable reference genes for the normalisation of gene expressio...
Abstract Background Macrophages are key players in the initiation, perpetuation and regulation of both innate and adaptive immune responses. They largely perform these roles... -
The face of Ebola: changing frequency of haemorrhage in the West African comp...
Abstract Background The West-African (WA) Zaire Ebolavirus disease (EVD) outbreak was characterized by an exceptionally high number of cases and deaths as compared with the... -
Involving general practice trainees in clinical practice guideline adaptation
Abstract Background It is unclear whether it is feasible to involve residents in guideline development or adaptation. We designed a multifaceted training program that combines... -
Avelumab in patients with previously treated metastatic melanoma: phase 1b re...
Abstract Background We report phase 1b data from patients enrolled in the JAVELIN Solid Tumor clinical trial (NCT01772004) with unresectable stage IIIC or IV melanoma that had... -
SEA-MAKE score as a tool for predicting major adverse kidney events in critic...
Abstract Background Acute kidney injury (AKI) is a common problem in critically ill patients and associated with high rates of morbidity and mortality. Recently, Major Adverse... -
Diabetic retinopathy is associated with the presence and burden of subclinica...
Abstract Background Cardiovascular (CV) disease due to atherosclerosis is a major cause of morbidity and mortality in adult patients with diabetes, either type 1 or type 2... -
Access to cardiac rehabilitation and the role of language barriers in the pro...
Abstract Background Cardiac rehabilitation (CR) has proven health benefits and, according to international guidelines, CR must be offered to all eligible patients. Studies have... -
Estimating the total prevalence and incidence of end-stage kidney disease amo...
Abstract Background Most estimates for End Stage Kidney Disease (ESKD) prevalence and incidence are based on renal replacement therapy (RRT) registers. However, not all people...
