27 items found

Types: other Tags: Genetics Medicine Neuroscience mesheuropmc.eye diseases

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    Eye Biometry Using Quantitatve 3-D OCT

    Cataracts cause the crystalline lens of the eye to progressively lose its transparency, which decreases vision. It is one of the major causes of vision loss in our aging...
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    Twenty-five years of optical coherence tomography: the paradigm shift in sens...

    Optical coherence tomography (OCT) has become one of the most successful optical technologies implemented in medicine and clinical practice mostly due to the possibility of...
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    Multimodal adaptive optics retinal imager: design and performance

    Optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO) are complementary imaging modalities, the combination of which can provide clinicians with a wealth of...
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    Extracellular vesicles derived from human ES-MSCs protect retinal ganglion ce...

    Abstract Background Retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (RGC) degeneration. There have been extensive...
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    Vision-related quality of life considering both eyes: results from the German...

    Abstract Purpose Most definitions of visual impairment focus on the status of the better-seeing eye only, but this approach might underestimate the influence of the worse-seeing...
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    The neuroregenerative effects of topical decorin on the injured mouse cornea

    Abstract Background The cornea is innervated with a rich supply of sensory nerves that play important roles in ocular surface health. Any injury or pathology of the corneal...
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    Retinal glial responses to optic nerve crush are attenuated in Bax-deficient ...

    Abstract Background Retinal ganglion cell (RGC) soma death is a consequence of optic nerve damage, including in optic neuropathies like glaucoma. The activation of the innate...
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    The association between socioeconomic status and visual impairments among pri...

    Abstract Background Glaucoma is one of the most leading causes of permanent visual impairments in Korea, and social expenses spent for the glaucoma are increasing. This study is...
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    Temporal multiplexing with adaptive optics for simultaneous vision

    We present and test a methodology for generating simultaneous vision with a deformable mirror that changed shape at 50 Hz between two vergences: 0 D (far vision) and −2.5 D...
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    Not only dominant, not only optic atrophy: expanding the clinical spectrum as...

    Abstract Background Heterozygous mutations in OPA1 are a common cause of autosomal dominant optic atrophy, sometimes associated with extra-ocular manifestations. Few cases...
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    Choroidal vascular changes in retinitis pigmentosa patients detected by optic...

    Abstract Background To evaluate choroidal vascular changes, including choriocapillaris (CC) and middle/large choroidal vessels, in retinitis pigmentosa (RP) patients using...
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    Postural effects on intraocular pressure and ocular perfusion pressure in pat...

    Abstract Background To investigate postural effects on intraocular pressure (IOP) and ocular perfusion pressure (OPP) in patients with non-arteritic ischemic optic neuropathy...
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    <i>CYP1B1</i> mutational screening in a Portuguese cohort of primary congenit...

    CYP1B1 mutational screening in a Portuguese cohort of primary congenital glaucoma patients
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    Macular evaluation of the retinal and choroidal vasculature changes in anteri...

    Abstract Background This study aimes to characterize the fundus structural changes in patients with nonarteritic anterior ischemic optic neuropathy (NAION) and the correlation...
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    X-linked inheritances recessive of congenital nystagmus and autosomal dominan...

    Abstract Background Congenital nystagmus (CN) and congenital cataracts are distinct eye diseases and are usually isolated. Cases with CN and congenital cataracts caused by...
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    Novel compound heterozygous mutations in CNGA1in a Chinese family affected wi...

    Abstract Background About 37 genes have been reported to be involved in autosomal recessive retinitis pigmentosa, a hereditary retinal disease. However, causative genes remain...
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    Human Herpesvirus-6 corneal Endotheliitis after intravitreal injection of Ran...

    Abstract Background To report the first case of human herpesvirus-6 (HHV-6) corneal endotheliitis that developed after intravitreal ranibizumab injections. Case presentation A...
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    In vivo optical frequency domain imaging of human retina and choroid

    Optical frequency domain imaging (OFDI) using swept laser sources is an emerging second-generation method for optical coherence tomography (OCT). Despite the widespread use of...
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    Microperimetry as a diagnostic tool for the detection of early, subclinical r...

    Abstract Background A majority of multiple sclerosis patients experience visual impairment, often as the initial presenting symptom of the disease. While structural changes in...
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    Phase-sensitive imaging of the outer retina using optical coherence tomograph...

    The cone photoreceptor’s outer segment (OS) experiences changes in optical path length, both in response to visible stimuli and as a matter of its daily course of renewal and...