389 items found

Types: other Tags: Developmental Biology Neuroscience

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    MRI of trunk muscles and motor and respiratory function in patients with myot...

    Abstract Background Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to...
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    Prevalence and characteristics of older adults with a persistent death wish w...

    Abstract Background Some older persons develop a persistent death wish without being severely ill, often referred to as “completed life” or “tiredness of life”. In the...
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    Genotype-phenotype correlations of adult-onset PLA2G6-associated Neurodegener...

    Abstract Background Phospholipase A2 group VI (PLA2G6) mutations associated with neurodegeneration (PLAN) manifest as heterogeneous neurodegenerative disorders with variable...
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    Pleural effusion from intrathoracic migration of a ventriculo-peritoneal shun...

    Abstract Background Pleural effusion is a rare complication of ventriculo-peritoneal (VP) cerebrospinal fluid (CSF) shunting and its diagnosis is difficult in patients with...
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    Characterization of a thalamic nucleus mediating habenula responses to change...

    Abstract Background Neural activity in the vertebrate habenula is affected by ambient illumination. The nucleus that links photoreceptor activity with the habenula is not well...
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    Cortical vein thrombosis in adult patients of cerebral venous sinus thrombosi...

    Abstract Background Cortical vein thrombosis (CVT) receives little attention in adult patients with cerebral venous sinus thrombosis (CVST). This study aimed to investigate the...
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    How to deal with a temporary suspension and restarting your trial: our experi...

    Abstract Whilst the issues around early termination of randomised controlled trials (RCTs) are well documented in the literature, trials can also be temporarily suspended with...
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    Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation t...

    Abstract Background Assessment of eye irritation hazard has long been a core requirement in any chemical legislation. Nevertheless, publications focussing on the eye damaging...
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    Analysis of hippocampal-dependent learning and memory behaviour in mice lacki...

    Abstract Objective The active place avoidance task (APA) is a behavioural task used to assess learning and memory in rodents. This task relies on the hippocampus, a region of...
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    Removal of the product from the culture medium strongly enhances free fatty a...

    Abstract Background Cyanobacterial mutants engineered for production of free fatty acids (FFAs) secrete the products to the medium and hence are thought to be useful for biofuel...
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    Resveratrol mediates mechanical allodynia through modulating inflammatory res...

    Abstract Background Neuropathic pain (NeuP) is a chronic and challenging clinical problem, with little effective treatment. Resveratrol has shown neuroprotection by inhibiting...
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    Long-term Safety and Efficacy of Human-Induced Pluripotent Stem Cell (iPS) Gr...

    Abstract The U.S. Food and Drug Administration recently approved phase I/II clinical trials for embryonic stem (ES) cell-based retinal pigmented epithelium (RPE)...
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    Diaper dermatitis: a survey of risk factors in Thai children aged under 24 mo...

    Abstract Background To identify the prevalence and risk factors associated with diaper dermatitis in Thai children aged 1–24 months. Methods This was a cross-sectional study of...
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    Evaluation of EMG pattern recognition for upper limb prosthesis control: a ca...

    Abstract Background Although electromyogram (EMG) pattern recognition (PR) for multifunctional upper limb prosthesis control has been reported for decades, the clinical benefits...
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    Psychiatric symptoms and risk factors in adults born preterm with very low bi...

    Abstract Background We aimed to examine psychiatric symptoms in adults born preterm with very low birthweight or born at term small for gestational age compared with normal...
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    Perioperative surgery- and anaesthesia-related risks of laparoscopic Roux-en-...

    Abstract Background Conservative obesity treatment often leads to limited results. Bariatric surgery is highly efficient, but the candidates are at risk of developing...
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    Fluid removal associates with better outcomes in critically ill patients rece...

    Abstract Background Fluid overload is associated with morbidity and mortality in patients receiving renal replacement therapy (RRT). We aimed to explore whether fluid overload...
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    Efficacy of an aluminium triformate mouthrinse during the maintenance phase i...

    Abstract Background The aim of this prospective placebo-controlled pilot study was to evaluate short-term effects of a mouthrinse containing aluminium triformate (ATF) on...
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    Peripheral cathepsin L inhibition induces fat loss in C. elegans and mice thr...

    Abstract Background Cathepsin L and some other cathepsins have been implicated in the development of obesity in humans and mice. The functional inactivation of the proteases...
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    Changes in the volatiles, chemical components and antioxidant activities of C...

    Chinese jasmine tea, a type of flower-scented tea, is produced by repeatedly mixing the base tea with the aromatic flowers of Jasminum sambac. The aim of this study was to...