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Temporal trends of dialysis requiring acute kidney injury after orthotopic ca...
Abstract Background The epidemiology and outcomes of acute kidney injury (AKI) in prevalent non-renal solid organ transplant recipients is unknown. Methods We assessed the... -
Long-term survival and prognostic factors for locally advanced renal cell car...
Abstract Background Previous related studies have mainly focused on renal cell carcinoma (RCC) with venous tumor thrombus, specifically inferior vena cava tumor thrombus with... -
Selection of reliable reference genes for the normalisation of gene expressio...
Abstract Background Macrophages are key players in the initiation, perpetuation and regulation of both innate and adaptive immune responses. They largely perform these roles... -
Effects of cyclosporine A pretreatment of deceased organ donors on kidney gra...
Abstract Background Renal transplantation represents the treatment of choice of end-stage kidney disease. Delayed graft function (DGF) remains the most frequent complication... -
Sucroferric oxyhydroxide decreases serum phosphorus level and fibroblast grow...
Abstract Objective Sucroferric oxyhydroxide, a novel iron-based phosphate-binder, has been shown to have beneficial effects in lowering serum phosphorus levels and improving... -
The challenge of managing mild to moderate distress in patients with end stag...
Abstract Background Lower-level emotional and psychological difficulties (‘distress’) in patients with end stage renal disease (ESRD), can lead to reduced quality of life and... -
Induction of the immunoprotective coat of Yersinia pestis at body temperature...
Abstract Background Thermal regulation of gene expression occurs in many microorganisms, and is mediated via several typical mechanisms. Yersinia pestis is the causative agent... -
Association of adipokines with blood pressure, arterial elasticity and cardia...
Abstract Background Adipokines are a set of cytokines secreted by white adipose tissue that have been suggested to be involved in the development of cardiovascular diseases. We... -
Urinary chitinase 3-like protein 1 for early diagnosis of acute kidney injury...
Abstract Background Acute kidney injury (AKI) occurs frequently and adversely affects patient and kidney outcomes, especially when its severity increases from stage 1 to stages... -
Association between furosemide administration and outcomes in critically ill ...
Abstract Background Although current guidelines for AKI suggested against the use of furosemide in AKI management, the effect of furosemide on outcomes in real-world clinical... -
Inhibition of Salmonella Typhimurium adhesion, invasion, and intracellular su...
Abstract Salmonella enterica serovar Typhimurium infects intestinal epithelia and macrophages, which is prevented by inhibiting adhesion and cell invasion. This study aimed to... -
Multiphoton in vivo imaging with a femtosecond semiconductor disk laser
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped... -
Performance of cytokine models in predicting SLE activity
Abstract Background Identification of universal biomarkers to predict systemic lupus erythematosus (SLE) flares is challenging due to the heterogeneity of the disease. Several... -
Knockout of interleukin-17A protects against sepsis-associated acute kidney i...
Abstract Background Sepsis-associated acute kidney injury (SA-AKI) is an independent risk factor for death in patients with sepsis, but treatment for it is limited. To improve... -
Reduced expression of miR-146a in human bronchial epithelial cells alters neu...
Abstract Background The role of miRNAs in the pathogenesis and determining the phenotypes of asthma is not fully elucidated. miR-146a has been previously shown to suppress... -
Downregulation of miR-204 expression defines a highly aggressive subset of Gr...
Abstract Genome-wide expression profiling studies have identified four core molecular subgroups of medulloblastoma: WNT, SHH, Group 3 and Group 4. Molecular markers are... -
Horizontal gene transfer is not a hallmark of the human genome
Abstract Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as... -
Risk factors for new-onset diabetes mellitus after living donor kidney transp...
Abstract Background New-onset diabetes mellitus after transplantation (NODAT) is a serious complication following renal transplantation. The aim of this study was to identify... -
Production of human pro-relaxin H2 in the yeast Pichia pastoris
Abstract Background Initially known as the reproductive hormone, relaxin was shown to possess other therapeutically useful properties that include extracellular matrix... -
Association between hydroxocobalamin administration and acute kidney injury a...
Abstract Background The use of hydroxocobalamin has long been advocated for treating suspected cyanide poisoning after smoke inhalation. Intravenous hydroxocobalamin has however...
