330 items found

Types: other Tags: Cancer Developmental Biology Physiology Science Policy

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    Analysis of survival after initiation of continuous renal replacement therapy...

    Abstract Background No study has specifically investigated the duration of continuous renal replacement therapy (CRRT) in patients who experienced acute kidney injury during...
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    MRI of trunk muscles and motor and respiratory function in patients with myot...

    Abstract Background Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to...
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    Pleural effusion from intrathoracic migration of a ventriculo-peritoneal shun...

    Abstract Background Pleural effusion is a rare complication of ventriculo-peritoneal (VP) cerebrospinal fluid (CSF) shunting and its diagnosis is difficult in patients with...
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    How to deal with a temporary suspension and restarting your trial: our experi...

    Abstract Whilst the issues around early termination of randomised controlled trials (RCTs) are well documented in the literature, trials can also be temporarily suspended with...
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    Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen...

    Abstract Background Nuclear receptor family member, Estrogen related receptor β, and the Hedgehog signal transduction pathway are both reported to relate to tumorigenesis and...
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    Unique patterns of lower respiratory tract microbiota are associated with inf...

    Abstract Background The lung microbiome maintains the homeostasis of the immune system within the lungs. In acute respiratory distress syndrome (ARDS), the lung microbiome is...
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    Vasoresponsiveness in patients with heart failure (VASOR): protocol for a pro...

    Abstract Background Vasoplegia is a severe complication which may occur after cardiac surgery, particularly in patients with heart failure. It is a result of activation of...
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    The whole - genome expression analysis of peripheral blood mononuclear cells ...

    Abstract Background Up to 30 % of adults with severe asthma are hypersensitive to aspirin and no unambiguous theory exists which provides a satisfactory explanation for the...
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    Resveratrol mediates mechanical allodynia through modulating inflammatory res...

    Abstract Background Neuropathic pain (NeuP) is a chronic and challenging clinical problem, with little effective treatment. Resveratrol has shown neuroprotection by inhibiting...
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    Periostin involved in the activated hepatic stellate cells-induced progressio...

    Abstract Background Incomplete thermal ablation may induce invasiveness of hepatocellular carcinoma (HCC). Here, we investigated whether activated hepatic stellate cells (HSCs)...
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    High cholesterol induces apoptosis and autophagy through the ROS-activated AK...

    Abstract Background Hypercholesterolemia increases the risk of tendon pain and tendon rupture. Tendon-derived stem cells (TDSCs) play a vital role in the development of...
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    Modified bolster dressing with continuous suction improves skin graft surviva...

    Abstract Background Skin engraftment of intraoral defects is known to be inconsistent due to mobility of the oral structure, uneven wounds, and accumulation of saliva under the...
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    Highly active promoters and native secretion signals for protein production d...

    Abstract Background The filamentous ascomycete Aspergillus niger is used in many industrial processes for the production of enzymes and organic acids by batch and fed-batch...
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    RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling p...

    Abstract Background Runt-related transcription factor 1 (RUNX1) plays the roles of an oncogene and an anti-oncogene in epithelial tumours, and abnormally elevated RUNX1 has been...
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    Prevention of multiple system atrophy using human bone marrow-derived mesench...

    Abstract Background Multiple system atrophy (MSA) is a sporadic neurodegenerative disorder of unknown etiology, but is closely associated with damage to dopaminergic neurons....
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    Association between ultrasound-detected synovitis and knee pain: a population...

    Abstract Background An important role for synovial pathology in the initiation and progression of knee osteoarthritis has been emphasised recently. This study aimed to examine...
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    Factors influencing decision regret regarding placement of a PEG among substi...

    Abstract Background A tube feeding decision aid designed at the Ottawa Health Research Institute was specifically created for substitute decision-makers who must decide whether...
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    Bacterial communities and metabolic activity of faecal cultures from equol pr...

    Abstract Background Isoflavones are polyphenols with estrogenic activity found mainly in soy and soy-derived products that need to be metabolised in the intestine by the gut...
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    The decline of FGM in Egypt since 1987: a cohort analysis of the Egypt Demogr...

    Abstract Background Female genital mutilation (FGM) has been a longstanding tradition in Egypt and until recently the practice was quasi-universal. Nevertheless, there are...
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    MiR-1-3p that correlates with left ventricular function of HCM can serve as a...

    Abstract Background MicroRNAs (miRNAs) are non-coding RNAs that function as regulators of gene expression and thereby contribute to the complex disease phenotypes. Hypertrophic...