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Periostin involved in the activated hepatic stellate cells-induced progressio...
Abstract Background Incomplete thermal ablation may induce invasiveness of hepatocellular carcinoma (HCC). Here, we investigated whether activated hepatic stellate cells (HSCs)... -
TNFAIP3 is required for FGFR1 activation-promoted proliferation and tumorigen...
Abstract Background Although ductal carcinoma in situ (DCIS) is a non-invasive breast cancer, many DCIS lesions may progress to invasive cancer and the genes and pathways... -
Astragaloside IV inhibits lung cancer progression and metastasis by modulatin...
Abstract Background Accumulating evidence suggests that M2-polarized tumor-associated macrophages (TAMs) play an important role in cancer progression and metastasis, making M2... -
Estrogen promotes estrogen receptor negative BRCA1-deficient tumor initiation...
Abstract Background Estrogen promotes breast cancer development and progression mainly through estrogen receptor (ER). However, blockage of estrogen production or action... -
AKT1 restricts the invasive capacity of head and neck carcinoma cells harbori...
Abstract Background In mammals, the AKT/PKB protein kinase family comprises three members (AKT1–3). PI3-Kinase (PI3K), a key oncogene involved in a wide variety of cancers,... -
Design and Implementation of a postgraduate curriculum to support Ethiopia's ...
Abstract Background To design and implement an emergency medicine (EM) postgraduate training curriculum to support the establishment of the first EM residency program at Addis... -
CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development
Abstract Background Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe... -
Age-specific incidence of allergic and non-allergic asthma
Abstract Background Onset of allergic asthma has a strong association with childhood but only a few studies have analyzed incidence of asthma from childhood to late adulthood in... -
A randomised clinical trial of a metaphylactic treatment with tildipirosin fo...
Abstract Background Bovine respiratory disease (BRD) is a major problem in veal calf rearing units. The objective of this randomised clinical trial was to assess the... -
Comparative efficacy of vasoactive medications in patients with septic shock:...
Abstract Background Catecholamines, especially norepinephrine, are the most frequently used vasopressors for treating patients with septic shock. During the recent decades,...
